Abstract
A genetic technique has been developed for isolating nuclear hybrids which are products of fusion between karyoplasts and whole cells. Nuclear hybrids have a greatly reduced mitochondrial component obtained from the nuclear donor and exhibit differences when compared to the corresponding whole-cell hybrids, such as better long-term survival and accelerated chromosome segregation. These results suggest that divergent mitochondria in a cell-fusion product may have adverse effects on survival.
Original language | English (US) |
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Pages (from-to) | 15-21 |
Number of pages | 7 |
Journal | Somatic Cell Genetics |
Volume | 8 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1982 |
ASJC Scopus subject areas
- Genetics