Abstract
Purpose: We have investigated a new technology for fabricating phantoms with fine details for use in small-animal imaging. Procedures: We used a high-resolution, 3-D stereolithography (SL) system to produce performance-evaluation phantoms such as cold-rod Derenzo, hot-channel Derenzo, and Defrise phantoms. SL performance was estimated by measuring the dimensions of many structures using a microscope. We also evaluated the degree of water absorption by two different SL resins, Somos® 11120 and Accura® 40, after curing. Results: The average bias and precision of the cold-rod structures over the size range 0.5 to 1.0 mm, were -0.4% and 1.74%, respectively. The water absorption study showed that Somos® 11120 is a more suitable material for nuclear medicine applications. Conclusion: We have demonstrated that SL is a robust and accurate method for fabrication of phantoms for small-animal imaging systems.
Original language | English (US) |
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Pages (from-to) | 231-236 |
Number of pages | 6 |
Journal | Molecular Imaging and Biology |
Volume | 10 |
Issue number | 5 |
DOIs | |
State | Published - 2008 |
Externally published | Yes |
Keywords
- MicroCT
- MicroMRI
- MicroPET
- MicroSPECT
- Molecular imaging
- Phantom
- Quality control
- Small-animal imaging
- Stereolithography
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
- Cancer Research