Christine J. Choe, Graham J. Emslie, Taryn L. Mayes

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


This article reviews the assessment and treatment for depression in children and adolescents, emphasizing the implementation of evidence-based treatments into clinical care. Past trials of antidepressant medications are reviewed, as well as the clinical use of antidepressants and pharmacologic strategies for refractory illness or in the context of comorbid conditions. Clinicians who treat youth now have a body of empiric research to help guide treatment decisions; however, personalized treatment based on associated symptoms, comorbid conditions, contextual factors, and psychiatric history is essential. Further research is needed in the pharmacologic treatment of depressed youth, including expanding the study of non-SSRI antidepressants, augmentation and adjunctive strategies, and treatment in patients with comorbid conditions.

Original languageEnglish (US)
Pages (from-to)807-829
Number of pages23
JournalChild and Adolescent Psychiatric Clinics of North America
Issue number4
StatePublished - Oct 2012


  • Antidepression treatment
  • Depression
  • MDD
  • Psychopharmacotherapy
  • Youth depression

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Psychiatry and Mental health


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