Demonstration of ponto-geniculo-occipital waves in the albino rat

G. A. Marks; J. Farber; M. Rubinstein; H. P. Roffwarg

doi:10.1016/0014-4886(80)90058-8

Demonstration of ponto-geniculo-occipital waves in the albino rat

G. A. Marks, J. Farber, M. Rubinstein, H. P. Roffwarg

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Monophasic waves that resemble the ponto-geniculo-occipital (PGO) waves recorded in cats were electrophysiologically recorded in the albino rat. These waves were most prominent within rapid eye movement (REM) sleep episodes and in the segments of slow-wave sleep just preceding both REM sleep periods and spontaneous awakenings. Administration of para-chlorophenylalanine (300 mg/kg) caused a change in distribution of the waves—an increase in the proportion occurring in waking and a decrease in REM sleep. REM sleep deprivation carried out by hand awakenings caused an increase in the proportion of waves occurring prior to REM sleep onset as well as a decrease in the proportion of waves in REM sleep. The waves recorded in the albino rat were so similar in their appearance to the PGO waves recorded in the cat as well as in their temporal distribution, and susceptibility to manipulation, that this activity appeared to constitute the rat homolog of PGO waves.

Original language	English (US)
Pages (from-to)	648-666
Number of pages	19
Journal	Experimental Neurology
Volume	69
Issue number	3
DOIs	https://doi.org/10.1016/0014-4886(80)90058-8
State	Published - 1980

Keywords

AW
AW-2
EEG
EMG
EOG
PCPA
PGO
R-2
REM
SW
SW sleep in the 2-min period before REM sleep onset
SW sleep in the 2-min period before spontaneous awakenings
awake
dl-para-chlorophenylalanine
electroencephalogram
electromyogram
electrooculogram
ponto-geniculo-occipital
rapid eye movement
slow wave

ASJC Scopus subject areas

Neurology
Developmental Neuroscience

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10.1016/0014-4886(80)90058-8

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@article{baf0a02505d845dab42b5f6cef622fc2,

title = "Demonstration of ponto-geniculo-occipital waves in the albino rat",

abstract = "Monophasic waves that resemble the ponto-geniculo-occipital (PGO) waves recorded in cats were electrophysiologically recorded in the albino rat. These waves were most prominent within rapid eye movement (REM) sleep episodes and in the segments of slow-wave sleep just preceding both REM sleep periods and spontaneous awakenings. Administration of para-chlorophenylalanine (300 mg/kg) caused a change in distribution of the waves—an increase in the proportion occurring in waking and a decrease in REM sleep. REM sleep deprivation carried out by hand awakenings caused an increase in the proportion of waves occurring prior to REM sleep onset as well as a decrease in the proportion of waves in REM sleep. The waves recorded in the albino rat were so similar in their appearance to the PGO waves recorded in the cat as well as in their temporal distribution, and susceptibility to manipulation, that this activity appeared to constitute the rat homolog of PGO waves.",

keywords = "AW, AW-2, EEG, EMG, EOG, PCPA, PGO, R-2, REM, SW, SW sleep in the 2-min period before REM sleep onset, SW sleep in the 2-min period before spontaneous awakenings, awake, dl-para-chlorophenylalanine, electroencephalogram, electromyogram, electrooculogram, ponto-geniculo-occipital, rapid eye movement, slow wave",

author = "Marks, {G. A.} and J. Farber and M. Rubinstein and Roffwarg, {H. P.}",

note = "Funding Information: Abbreviations: PGO-ponto-geniculo-occipital, REM-rapid eye movement, SW-slow wave, EEG-electroencephalogram, EMG-electromyogram, EOG-electrooculogram, PCPA-dl-para-chlorophenylalanine, AW-awake, R-2-SW sleep in the 2-min period before REM sleep onset, AW-2-SW sleep in the 2-min period before spontaneous awakenings. {\textquoteright} This work was supported by National Institute of Mental Health grant MH3 1402 (H.P.R.), the Alfred P. Sloan Research Fellowship (J.F.), and the Public Health Service Biomedical Research support grant 666673 (G.M.). Please address reprint requests to Dr. G. A. Marks, University of Texas Health Science Center, Department of Psychiatry, 5323 Harry Hines Boulevard, Dallas, TX 75235.",

year = "1980",

doi = "10.1016/0014-4886(80)90058-8",

language = "English (US)",

volume = "69",

pages = "648--666",

journal = "Experimental Neurology",

issn = "0014-4886",

publisher = "Academic Press Inc.",

number = "3",

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TY - JOUR

T1 - Demonstration of ponto-geniculo-occipital waves in the albino rat

AU - Marks, G. A.

AU - Farber, J.

AU - Rubinstein, M.

AU - Roffwarg, H. P.

N1 - Funding Information: Abbreviations: PGO-ponto-geniculo-occipital, REM-rapid eye movement, SW-slow wave, EEG-electroencephalogram, EMG-electromyogram, EOG-electrooculogram, PCPA-dl-para-chlorophenylalanine, AW-awake, R-2-SW sleep in the 2-min period before REM sleep onset, AW-2-SW sleep in the 2-min period before spontaneous awakenings. ’ This work was supported by National Institute of Mental Health grant MH3 1402 (H.P.R.), the Alfred P. Sloan Research Fellowship (J.F.), and the Public Health Service Biomedical Research support grant 666673 (G.M.). Please address reprint requests to Dr. G. A. Marks, University of Texas Health Science Center, Department of Psychiatry, 5323 Harry Hines Boulevard, Dallas, TX 75235.

PY - 1980

Y1 - 1980

N2 - Monophasic waves that resemble the ponto-geniculo-occipital (PGO) waves recorded in cats were electrophysiologically recorded in the albino rat. These waves were most prominent within rapid eye movement (REM) sleep episodes and in the segments of slow-wave sleep just preceding both REM sleep periods and spontaneous awakenings. Administration of para-chlorophenylalanine (300 mg/kg) caused a change in distribution of the waves—an increase in the proportion occurring in waking and a decrease in REM sleep. REM sleep deprivation carried out by hand awakenings caused an increase in the proportion of waves occurring prior to REM sleep onset as well as a decrease in the proportion of waves in REM sleep. The waves recorded in the albino rat were so similar in their appearance to the PGO waves recorded in the cat as well as in their temporal distribution, and susceptibility to manipulation, that this activity appeared to constitute the rat homolog of PGO waves.

AB - Monophasic waves that resemble the ponto-geniculo-occipital (PGO) waves recorded in cats were electrophysiologically recorded in the albino rat. These waves were most prominent within rapid eye movement (REM) sleep episodes and in the segments of slow-wave sleep just preceding both REM sleep periods and spontaneous awakenings. Administration of para-chlorophenylalanine (300 mg/kg) caused a change in distribution of the waves—an increase in the proportion occurring in waking and a decrease in REM sleep. REM sleep deprivation carried out by hand awakenings caused an increase in the proportion of waves occurring prior to REM sleep onset as well as a decrease in the proportion of waves in REM sleep. The waves recorded in the albino rat were so similar in their appearance to the PGO waves recorded in the cat as well as in their temporal distribution, and susceptibility to manipulation, that this activity appeared to constitute the rat homolog of PGO waves.

KW - AW

KW - AW-2

KW - EEG

KW - EMG

KW - EOG

KW - PCPA

KW - PGO

KW - R-2

KW - REM

KW - SW

KW - SW sleep in the 2-min period before REM sleep onset

KW - SW sleep in the 2-min period before spontaneous awakenings

KW - awake

KW - dl-para-chlorophenylalanine

KW - electroencephalogram

KW - electromyogram

KW - electrooculogram

KW - ponto-geniculo-occipital

KW - rapid eye movement

KW - slow wave

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DO - 10.1016/0014-4886(80)90058-8

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C2 - 6447612

AN - SCOPUS:0018959721

SN - 0014-4886

VL - 69

SP - 648

EP - 666

JO - Experimental Neurology

JF - Experimental Neurology

IS - 3

ER -

Demonstration of ponto-geniculo-occipital waves in the albino rat

Abstract

Keywords

ASJC Scopus subject areas

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