Delayed Puberty and Amenorrhea

Barbara Hoffman, Karen D. Bradshaw

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


The ability to diagnose and manage disorders that cause delayed puberty requires a thorough understanding of the physical and hormonal events of puberty. Wide variation exists within normal pubertal maturation, but most adolescent girls in the United States have begun to mature by the age of 13. Delayed puberty, a rare condition in girls, occurs in only ∼2.5% of the population. Constitutional delay, genetic defects, or hypothalamic-pituitary disorders are common causes. Amenorrhea, often found as a symptom of delayed puberty, may be due to congenital genital tract anomalies, ovarian failure, or chronic anovulation with estrogen presence or with estrogen absence.

Original languageEnglish (US)
Pages (from-to)353-362
Number of pages10
JournalSeminars in reproductive medicine
Issue number4
StatePublished - Nov 1 2003


  • Delayed
  • Primary and secondary amenorrhea
  • Puberty

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Reproductive Medicine
  • Endocrinology
  • Obstetrics and Gynecology
  • Physiology (medical)


Dive into the research topics of 'Delayed Puberty and Amenorrhea'. Together they form a unique fingerprint.

Cite this