Definitions and outcome measures for bullous pemphigoid: Recommendations by an international panel of experts

Dedee F. Murrell, Benjamin S. Daniel, Pascal Joly, Luca Borradori, Masayuki Amagai, Takashi Hashimoto, Frédéric Caux, Branka Marinovic, Animesh A. Sinha, Michael Hertl, Philippe Bernard, David Sirois, Giuseppe Cianchini, Janet A. Fairley, Marcel F. Jonkman, Amit G. Pandya, David Rubenstein, Detlef Zillikens, Aimee S. Payne, David WoodleyGiovanna Zambruno, Valeria Aoki, Carlo Pincelli, Luis Diaz, Russell P. Hall, Michael Meurer, Jose M. Mascaro, Enno Schmidt, Hiroshi Shimizu, John Zone, Robert Swerlick, Daniel Mimouni, Donna Culton, Jasna Lipozencic, Benjamin Bince, Sergei A. Grando, Jean Claude Bystryn, Victoria P. Werth

Research output: Contribution to journalReview articlepeer-review

279 Scopus citations


Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sharing multicenter-based evidences for therapeutic efforts is the lack of generally accepted definitions for the clinical evaluation of patients with BP. Common terms and end points of BP are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. These recommendations from the International Pemphigoid Committee represent 2 years of collaborative efforts to attain mutually acceptable common definitions for BP and proposes a disease extent score, the BP Disease Area Index. These items should assist in the development of consistent reporting of outcomes in future BP reports and studies.

Original languageEnglish (US)
Pages (from-to)479-485
Number of pages7
JournalJournal of the American Academy of Dermatology
Issue number3
StatePublished - Mar 2012


  • bullous pemphigoid
  • consensus
  • definitions
  • outcome measures
  • severity score

ASJC Scopus subject areas

  • Dermatology


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