Cytodiagnosis of a primary effusion lymphoma: A case report

Manjunath S. Vadmal; Thorn F. Smilari; Judith P. Brody; Prasad Koduru; Steven I. Hajdu

doi:10.1159/000331619

Cytodiagnosis of a primary effusion lymphoma: A case report

Manjunath S. Vadmal, Thorn F. Smilari, Judith P. Brody, Prasad Koduru, Steven I. Hajdu

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

BACKGROUND: Primary effusion lymphoma (PEL), commonly described in AIDS patients, is a unique subset of lymphoma in which the neoplastic lymphocytes proliferate exclusively in serous cavities. CASE: A 27-year-old male, HIV positive for five years and with multiple opportunistic infections in the past, was admitted for sudden-onset shortness of breath caused by a pleural effusion. Cytologic examination of the pleural fluid revealed medium to large atypical lymphocytes with a high mitosis rate, suspicious for lymphoma. Further diagnostic tests, such as immunophenotypic analysis and cytogenetic and molecular studies, confirmed the diagnosis of PEL. CONCLUSION: Cytopathologists and cytotechnologists should be aware of this new entity since additional studies are required for a definitive diagnosis.

Original language	English (US)
Pages (from-to)	374-376
Number of pages	3
Journal	Acta Cytologica
Volume	42
Issue number	2
DOIs	https://doi.org/10.1159/000331619
State	Published - Jan 1 1998

Keywords

AIDS-associated lymphoma
Burkitt's translocation
Primary effusion lymphoma

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

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10.1159/000331619

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abstract = "BACKGROUND: Primary effusion lymphoma (PEL), commonly described in AIDS patients, is a unique subset of lymphoma in which the neoplastic lymphocytes proliferate exclusively in serous cavities. CASE: A 27-year-old male, HIV positive for five years and with multiple opportunistic infections in the past, was admitted for sudden-onset shortness of breath caused by a pleural effusion. Cytologic examination of the pleural fluid revealed medium to large atypical lymphocytes with a high mitosis rate, suspicious for lymphoma. Further diagnostic tests, such as immunophenotypic analysis and cytogenetic and molecular studies, confirmed the diagnosis of PEL. CONCLUSION: Cytopathologists and cytotechnologists should be aware of this new entity since additional studies are required for a definitive diagnosis.",

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AU - Vadmal, Manjunath S.

AU - Smilari, Thorn F.

AU - Brody, Judith P.

AU - Koduru, Prasad

AU - Hajdu, Steven I.

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AB - BACKGROUND: Primary effusion lymphoma (PEL), commonly described in AIDS patients, is a unique subset of lymphoma in which the neoplastic lymphocytes proliferate exclusively in serous cavities. CASE: A 27-year-old male, HIV positive for five years and with multiple opportunistic infections in the past, was admitted for sudden-onset shortness of breath caused by a pleural effusion. Cytologic examination of the pleural fluid revealed medium to large atypical lymphocytes with a high mitosis rate, suspicious for lymphoma. Further diagnostic tests, such as immunophenotypic analysis and cytogenetic and molecular studies, confirmed the diagnosis of PEL. CONCLUSION: Cytopathologists and cytotechnologists should be aware of this new entity since additional studies are required for a definitive diagnosis.

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Cytodiagnosis of a primary effusion lymphoma: A case report

Abstract

Keywords

ASJC Scopus subject areas

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