Current status of Duchenne muscular dystrophy

S. T. Iannaccone

doi:10.1016/S0031-3955(16)38379-1

Current status of Duchenne muscular dystrophy

S. T. Iannaccone

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Duchenne muscular dystrophy is the second most common lethal genetic disorder in humans. With the advent of molecular genetic technology, the definition of this disease has been modified to include an abnormality of dystrophin in muscle-a dystrophinopathy. Accurate genetic counseling is possible using methods of deletion detection and linkage analysis. Treatment of this type of muscular dystrophy may soon mean the routine use of steroids and later include direct injection of an artificial gene for dystrophin.

Original language	English (US)
Pages (from-to)	879-894
Number of pages	16
Journal	Pediatric clinics of North America
Volume	39
Issue number	4
DOIs	https://doi.org/10.1016/S0031-3955(16)38379-1
State	Published - 1992

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0031-3955(16)38379-1

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abstract = "Duchenne muscular dystrophy is the second most common lethal genetic disorder in humans. With the advent of molecular genetic technology, the definition of this disease has been modified to include an abnormality of dystrophin in muscle-a dystrophinopathy. Accurate genetic counseling is possible using methods of deletion detection and linkage analysis. Treatment of this type of muscular dystrophy may soon mean the routine use of steroids and later include direct injection of an artificial gene for dystrophin.",

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Current status of Duchenne muscular dystrophy

Abstract

ASJC Scopus subject areas

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