Current Perspectives and Practices on Chronic Total Occlusion Percutaneous Coronary Interventions

Siddharth M. Patel, Rohan V. Menon, M. Nicolas Burke, Farouc A. Jaffer, Robert W. Yeh, Minh Vo, DImitri Karmpaliotis, Lorenzo Azzalini, Mauro Carlino, Kambis Mashayekhi, Alfredo R. Galassi, Stephane Rinfret, Stephen G. Ellis, Mitul Patel, Bavana V. Rangan, Aris Karatasakis, Barbara A. Danek, Judit Karacsonyi, Erica Resendes, Subhash BanerjeeEmmanouil S. Brilakis

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


OBJECTIVES: We sought to examine contemporary perspectives and practices on chronic total occlusion (CTO) percutaneous coronary intervention (PCI). BACKGROUND: The frequency and success of CTO-PCI have been increasing in recent years. METHODS: An online questionnaire was created and distributed to cardiologists within the United States and internationally. RESULTS: A total of 1149 responses were obtained. The United States (n ≤ 845; 73.5%), Asia (n ≤ 98; 8.5%), Europe (n ≤ 88; 7.7%), South America (n ≤ 42; 3.7%), and Canada (n ≤ 33; 2.9%) accounted for most responses. Mean practice duration of the respondents was 16.4 ± 11.5 years and 66.9% were interventional cardiologists. Most respondents agreed that CTO-PCI results in an improvement of patient symptoms (90.7%), left ventricular function (79.3%), arrhythmia risk (69.2%), and overall survival (63.1%). Interventional cardiologists had a more favorable view of the benefits of CTO-PCI as compared with non-interventional cardiologists (P<.001). Most respondents estimated the procedural success rates of contemporary CTO-PCI to be between 51%-75% (34.2%) and 76%-85% (30.2%), with interventional cardiologists estimating higher success rates than non-interventionalists (P<.001). Perforation, mortality, and tamponade were the three most concerning complications. Time and procedure complexity were reported to be the most significant barriers to the development of a CTO-PCI program. CONCLUSIONS: Most cardiologists believe that CTO-PCI can provide significant clinical benefits and can be accomplished with moderate to high success rates. Interventional cardiologists have a more favorable view of CTO-PCI as compared with non-invasive cardiologists.

Original languageEnglish (US)
Pages (from-to)43-50
Number of pages8
JournalJournal of Invasive Cardiology
Issue number2
StatePublished - Feb 2018


  • chronic total occlusion
  • complications
  • percutaneous coronary intervention
  • procedural success
  • techniques

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Current Perspectives and Practices on Chronic Total Occlusion Percutaneous Coronary Interventions'. Together they form a unique fingerprint.

Cite this