CT and MRI findings in leptomeningeal melanocytosis

Ferzana A. Hossain, Hector J. Marquez, Daniel L. Veltkamp, Sophia Q. Xie, Laura J. Klesse, Charles F. Timmons, Cory M. Pfeifer

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Leptomeningeal melanocytosis is a rare cause of seizure in the pediatric population. Shown here is a case of this disease in a 9-year-old male who presented with seizures and minor trauma. Imaging showed progression of leptomeningeal enhancement in the setting of increased seizure activity, and biopsy confirmed the diagnosis. The patient received immunotherapy but eventually succumbed to the disease. This case serves as an educational tool to improve awareness of melanocytic proliferation as a differential consideration for leptomeningeal enhancement.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalRadiology Case Reports
Issue number3
StatePublished - Mar 2020


  • Leptomeningeal melanocytosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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