Corrigendum: Low-dose fentanyl reduces pain perception, muscle sympathetic nerve activity responses, and blood pressure responses during the cold pressor test (American Journal of Physiology - Regulatory Integrative and Comparative Physiology (2022) 322 (R64–R76) DOI: 10.1152/ajpregu.00218.2021)

Low-dose fentanyl reduces pain perception, muscle sympathetic nerve activity responses, and blood pressure responses during the cold pressor test. Am J Physiol Regul Integr Comp Physiol 322: R64–R76, 2022. First published December 1, 2021. doi: https://doi.org/10.1152/ajpregu.00218.2021. In the original article, five Cohen’s d effect size values were incorrect. Of the five corrections, the change in systolic blood pressure (BP) can be interpreted as a “small” rather than “medium” effect, whereas the other four corrections do not change the interpretation of the effect. This error does not change the scientific conclusions of the article. The correct sentences should read as follows: Page R68, under Postdrug Administration Pain Assessments: None of these participants reached our predetermined upper limit of 3 kg before, or after, fentanyl/placebo administration. Pain perception during the post-CPT was lower (Fig. 2; Cohen’s d = 1.65) after fentanyl compared with placebo administration. Page R68, under Postdrug Administration Sympathetic Measures: The magnitude of the increases in MSNA burst frequency (Cohen’s d = 1.06) and burst incidence during the post-CPT were attenuated following fentanyl compared with placebo trials (Fig. 4, B and D). Page R69, under Postdrug Administration Cardiovascular Measures: Increases in systolic BP during the post-CPT were 6 mmHg lower on average after fentanyl compared with placebo administration (Cohen’s d = 0.42, Fig. 5B). Increases in mean (Cohen’s d = 0.54) and diastolic (Cohen’s d = 0.56) BP during the post-CPT were also attenuated after fentanyl compared with placebo administration (Fig. 5, D and F).