Correlation of intrinsic chemoresistance of non-small-cell lung cancer cell lines with HER-2/neu gene expression but not with ras gene mutations

Medicine & Life Sciences

• 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide 12%
• Carmustine 19%
• Cell Line 42%
• Cell Proliferation 4%
• Cisplatin 13%
• Doxorubicin 13%
• Drug Resistance 6%
• erbB-2 Genes 100%
• Etoposide 15%
• Gene Expression 43%
• Genes 2%
• Growth 3%
• In Vitro Techniques 6%
• Inhibitory Concentration 50 19%
• Melphalan 17%
• Messenger RNA 4%
• Mitomycin 15%
• Multiple Drug Resistance 7%
• Mutation 40%
• Neoplasms 2%
• Non-Small Cell Lung Carcinoma 64%
• Pharmaceutical Preparations 8%
• Phenotype 4%
• Point Mutation 7%
• ras Genes 87%
• Small Cell Lung Carcinoma 15%
• Survival 3%
• Therapeutics 2%
• thiazolyl blue 8%
• Transcriptional Activation 13%