Abstract
The eye and the brain have limited capacities for regeneration and as such, immune-mediated inflammation can produce devastating consequences in the form of neurodegenerative diseases of the central nervous system or blindness as a result of ocular inflammatory diseases such as uveitis. Accordingly, both the eye and the brain are designed to limit immune responses and inflammation – a condition known as “immune privilege”. Immune privilege is sustained by physiological, anatomical, and regulatory processes that conspire to restrict both adaptive and innate immune responses.
Original language | English (US) |
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Article number | 701935 |
Journal | Frontiers in immunology |
Volume | 12 |
DOIs | |
State | Published - Jun 18 2021 |
Keywords
- contrasuppressor cells
- cornea
- dendritic cells
- immune privilege
- nerves
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology