Copper clusters-based luminescence assay for tetracycline and cellular imaging studies

Zhuosen Wang; Chengcheng Zhang; Jinwei Gao; Qianming Wang

doi:10.1016/j.jlumin.2017.05.038

Copper clusters-based luminescence assay for tetracycline and cellular imaging studies

Zhuosen Wang, Chengcheng Zhang, Jinwei Gao, Qianming Wang

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Two copper nanoclusters (NCs) stabilized by L-cysteine and glutathione have been reported. The nanoparticles with ultrafine size had excellent water solubility and exhibited green or red emission respectively. Particularly, the two copper clusters were found to be responsive to the presence of tetracycline (TC) and on-off quenching effects were achieved. After incubation, the cell staining and target-detection features could be still effective in two adherent live cells. The nanocluster showed very low cytotoxicity and excellent biological compatibility. Accordingly, the special photophysical properties of copper NCs will be attractive for various potential applications such as bio-sensing and medical diagnosis.

Original language	English (US)
Pages (from-to)	115-122
Number of pages	8
Journal	Journal of Luminescence
Volume	190
DOIs	https://doi.org/10.1016/j.jlumin.2017.05.038
State	Published - Oct 2017

Keywords

Cell imaging
Luminescence
Metal clusters
Probe

ASJC Scopus subject areas

Biophysics
Biochemistry
Chemistry(all)
Atomic and Molecular Physics, and Optics
Condensed Matter Physics

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10.1016/j.jlumin.2017.05.038

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title = "Copper clusters-based luminescence assay for tetracycline and cellular imaging studies",

abstract = "Two copper nanoclusters (NCs) stabilized by L-cysteine and glutathione have been reported. The nanoparticles with ultrafine size had excellent water solubility and exhibited green or red emission respectively. Particularly, the two copper clusters were found to be responsive to the presence of tetracycline (TC) and on-off quenching effects were achieved. After incubation, the cell staining and target-detection features could be still effective in two adherent live cells. The nanocluster showed very low cytotoxicity and excellent biological compatibility. Accordingly, the special photophysical properties of copper NCs will be attractive for various potential applications such as bio-sensing and medical diagnosis.",

keywords = "Cell imaging, Luminescence, Metal clusters, Probe",

author = "Zhuosen Wang and Chengcheng Zhang and Jinwei Gao and Qianming Wang",

year = "2017",

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doi = "10.1016/j.jlumin.2017.05.038",

language = "English (US)",

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journal = "Journal of Luminescence",

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T1 - Copper clusters-based luminescence assay for tetracycline and cellular imaging studies

AU - Wang, Zhuosen

AU - Zhang, Chengcheng

AU - Gao, Jinwei

AU - Wang, Qianming

PY - 2017/10

Y1 - 2017/10

N2 - Two copper nanoclusters (NCs) stabilized by L-cysteine and glutathione have been reported. The nanoparticles with ultrafine size had excellent water solubility and exhibited green or red emission respectively. Particularly, the two copper clusters were found to be responsive to the presence of tetracycline (TC) and on-off quenching effects were achieved. After incubation, the cell staining and target-detection features could be still effective in two adherent live cells. The nanocluster showed very low cytotoxicity and excellent biological compatibility. Accordingly, the special photophysical properties of copper NCs will be attractive for various potential applications such as bio-sensing and medical diagnosis.

AB - Two copper nanoclusters (NCs) stabilized by L-cysteine and glutathione have been reported. The nanoparticles with ultrafine size had excellent water solubility and exhibited green or red emission respectively. Particularly, the two copper clusters were found to be responsive to the presence of tetracycline (TC) and on-off quenching effects were achieved. After incubation, the cell staining and target-detection features could be still effective in two adherent live cells. The nanocluster showed very low cytotoxicity and excellent biological compatibility. Accordingly, the special photophysical properties of copper NCs will be attractive for various potential applications such as bio-sensing and medical diagnosis.

KW - Cell imaging

KW - Luminescence

KW - Metal clusters

KW - Probe

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M3 - Article

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SN - 0022-2313

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SP - 115

EP - 122

JO - Journal of Luminescence

JF - Journal of Luminescence

ER -

Copper clusters-based luminescence assay for tetracycline and cellular imaging studies

Abstract

Keywords

ASJC Scopus subject areas

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