@article{b7c07573b182463d8e9bb4ae58c1dff5,
title = "Contribution of Breastfeeding to False-Positive Saliva Polymerase Chain Reaction for Newborn Congenital Cytomegalovirus Screening",
abstract = "Real-time polymerase chain reaction (PCR) of saliva is highly sensitive for newborn congenital cytomegalovirus (CMV) screening. This study uses nationally published CMV seroprevalence and breastfeeding rates to estimate the contribution of CMV DNA in breast milk to false-positive saliva PCR results. The false-positive rates adjusted for breastfeeding ranged from 0.03% in white Hispanic persons to 0.14% in white non-Hispanic persons. Saliva CMV PCR for newborn screening is highly sensitive, and the low false-positive rates in this study suggest that saliva PCR results are unlikely to be significantly influenced by breastfeeding or other perinatal exposures.",
keywords = "breastfeeding, cytomegalovirus, newborn, polymerase chain reaction, saliva, screening",
author = "Ross, {Shannon A.} and Michaels, {Marian G.} and Amina Ahmed and Palmer, {April L.} and S{\'a}nchez, {Pablo J.} and Bernstein, {David I.} and Kristina Feja and Audra Stewart and Boppana, {Suresh B.} and Fowler, {Karen B.}",
note = "Funding Information: Financial Support. This work was supported by the National Institutes of Health (R01-DC012661-01 to S. A. R.; N01-DC50008 and HHS-N-263-2012-00010-C to S. B. B.; U01 -P000177, U01-DD-12-005, R01-HD61959, U01-AI103401-01, R01-DC012661-01, N01-DC50008, HHS-N-263-2012-00010-C to K. B. F.; N01-DC50008 to A. A.; N01-DC50008 to A. L. P.; N01-DC50008 to M. G. M.; N01-DC50008 to P. J. S.; and N01-DC50008 to D. I. B.) Potential conflicts of interest. All Authors: No reported conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed. Publisher Copyright: {\textcopyright} The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved.",
year = "2018",
month = apr,
day = "23",
doi = "10.1093/infdis/jiy057",
language = "English (US)",
volume = "217",
pages = "1612--1615",
journal = "The Journal of infectious diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "10",
}