Contrast-enhanced voiding urosonography, part 1: vesicoureteral reflux evaluation

Aikaterini Ntoulia; Elisa Aguirre Pascual; Susan J. Back; Richard D. Bellah; Viviana P. Beltrán Salazar; Pui Kwan Joyce Chan; Jeanne S. Chow; David Coca Robinot; Kassa Darge; Carmina Duran; Monica Epelman; Damjana Ključevšek; Jeannie K. Kwon; Preet Kiran Sandhu; Magdalena M. Woźniak; Frederica Papadopoulou

doi:10.1007/s00247-020-04906-8

Contrast-enhanced voiding urosonography, part 1: vesicoureteral reflux evaluation

Aikaterini Ntoulia, Elisa Aguirre Pascual, Susan J. Back, Richard D. Bellah, Viviana P. Beltrán Salazar, Pui Kwan Joyce Chan, Jeanne S. Chow, David Coca Robinot, Kassa Darge, Carmina Duran, Monica Epelman, Damjana Ključevšek, Jeannie K. Kwon, Preet Kiran Sandhu, Magdalena M. Woźniak, Frederica Papadopoulou

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Contrast-enhanced voiding urosonography (ceVUS) is a well-established, sensitive and safe ultrasound (US) modality for detecting and grading vesicoureteral reflux (VUR) and urethral imaging in children. Nearly three decades of remarkable advances in US technology and US contrast agents have refined ceVUS’s diagnostic potential. The recent approval of Lumason/SonoVue in the United States, Europe and China for pediatric intravesical applications marked the beginning of a new era for this type of contrast US imaging. Consequently, the use of ceVUS in children has expanded to multiple places around the globe. In the first part of this review article, we describe the current experience in the use of ceVUS for VUR evaluation, with an emphasis on historical background, examination technique, image interpretation and diagnostic accuracy. In the second part, we will present the role of ceVUS for urethral imaging in children.

Original language	English (US)
Pages (from-to)	2351-2367
Number of pages	17
Journal	Pediatric radiology
Volume	51
Issue number	12
DOIs	https://doi.org/10.1007/s00247-020-04906-8
State	Published - Nov 2021

Keywords

Children
Contrast-enhanced voiding urosonography
Ultrasound
Ultrasound contrast agents
Vesicoureteral reflux
Vesicoureteral reflux detection
Vesicoureteral reflux grading

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Radiology Nuclear Medicine and imaging

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Ntoulia, A., Aguirre Pascual, E., Back, S. J., Bellah, R. D., Beltrán Salazar, V. P., Chan, P. K. J., Chow, J. S., Coca Robinot, D., Darge, K., Duran, C., Epelman, M., Ključevšek, D., Kwon, J. K., Sandhu, P. K., Woźniak, M. M., & Papadopoulou, F. (2021). Contrast-enhanced voiding urosonography, part 1: vesicoureteral reflux evaluation. Pediatric radiology, 51(12), 2351-2367. https://doi.org/10.1007/s00247-020-04906-8

Ntoulia, A, Aguirre Pascual, E, Back, SJ, Bellah, RD, Beltrán Salazar, VP, Chan, PKJ, Chow, JS, Coca Robinot, D, Darge, K, Duran, C, Epelman, M, Ključevšek, D, Kwon, JK, Sandhu, PK, Woźniak, MM & Papadopoulou, F 2021, 'Contrast-enhanced voiding urosonography, part 1: vesicoureteral reflux evaluation', Pediatric radiology, vol. 51, no. 12, pp. 2351-2367. https://doi.org/10.1007/s00247-020-04906-8

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title = "Contrast-enhanced voiding urosonography, part 1: vesicoureteral reflux evaluation",

abstract = "Contrast-enhanced voiding urosonography (ceVUS) is a well-established, sensitive and safe ultrasound (US) modality for detecting and grading vesicoureteral reflux (VUR) and urethral imaging in children. Nearly three decades of remarkable advances in US technology and US contrast agents have refined ceVUS{\textquoteright}s diagnostic potential. The recent approval of Lumason/SonoVue in the United States, Europe and China for pediatric intravesical applications marked the beginning of a new era for this type of contrast US imaging. Consequently, the use of ceVUS in children has expanded to multiple places around the globe. In the first part of this review article, we describe the current experience in the use of ceVUS for VUR evaluation, with an emphasis on historical background, examination technique, image interpretation and diagnostic accuracy. In the second part, we will present the role of ceVUS for urethral imaging in children.",

keywords = "Children, Contrast-enhanced voiding urosonography, Ultrasound, Ultrasound contrast agents, Vesicoureteral reflux, Vesicoureteral reflux detection, Vesicoureteral reflux grading",

author = "Aikaterini Ntoulia and {Aguirre Pascual}, Elisa and Back, {Susan J.} and Bellah, {Richard D.} and {Beltr{\'a}n Salazar}, {Viviana P.} and Chan, {Pui Kwan Joyce} and Chow, {Jeanne S.} and {Coca Robinot}, David and Kassa Darge and Carmina Duran and Monica Epelman and Damjana Klju{\v c}ev{\v s}ek and Kwon, {Jeannie K.} and Sandhu, {Preet Kiran} and Wo{\'z}niak, {Magdalena M.} and Frederica Papadopoulou",

note = "Funding Information: Drs. Back and Darge received educational grants from Bracco Diagnostics. Publisher Copyright: {\textcopyright} 2021, Springer-Verlag GmbH Germany, part of Springer Nature.",

year = "2021",

month = nov,

doi = "10.1007/s00247-020-04906-8",

language = "English (US)",

volume = "51",

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AU - Ntoulia, Aikaterini

AU - Aguirre Pascual, Elisa

AU - Back, Susan J.

AU - Bellah, Richard D.

AU - Beltrán Salazar, Viviana P.

AU - Chan, Pui Kwan Joyce

AU - Chow, Jeanne S.

AU - Coca Robinot, David

AU - Darge, Kassa

AU - Duran, Carmina

AU - Epelman, Monica

AU - Ključevšek, Damjana

AU - Kwon, Jeannie K.

AU - Sandhu, Preet Kiran

AU - Woźniak, Magdalena M.

AU - Papadopoulou, Frederica

PY - 2021/11

Y1 - 2021/11

N2 - Contrast-enhanced voiding urosonography (ceVUS) is a well-established, sensitive and safe ultrasound (US) modality for detecting and grading vesicoureteral reflux (VUR) and urethral imaging in children. Nearly three decades of remarkable advances in US technology and US contrast agents have refined ceVUS’s diagnostic potential. The recent approval of Lumason/SonoVue in the United States, Europe and China for pediatric intravesical applications marked the beginning of a new era for this type of contrast US imaging. Consequently, the use of ceVUS in children has expanded to multiple places around the globe. In the first part of this review article, we describe the current experience in the use of ceVUS for VUR evaluation, with an emphasis on historical background, examination technique, image interpretation and diagnostic accuracy. In the second part, we will present the role of ceVUS for urethral imaging in children.

AB - Contrast-enhanced voiding urosonography (ceVUS) is a well-established, sensitive and safe ultrasound (US) modality for detecting and grading vesicoureteral reflux (VUR) and urethral imaging in children. Nearly three decades of remarkable advances in US technology and US contrast agents have refined ceVUS’s diagnostic potential. The recent approval of Lumason/SonoVue in the United States, Europe and China for pediatric intravesical applications marked the beginning of a new era for this type of contrast US imaging. Consequently, the use of ceVUS in children has expanded to multiple places around the globe. In the first part of this review article, we describe the current experience in the use of ceVUS for VUR evaluation, with an emphasis on historical background, examination technique, image interpretation and diagnostic accuracy. In the second part, we will present the role of ceVUS for urethral imaging in children.

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Contrast-enhanced voiding urosonography, part 1: vesicoureteral reflux evaluation

Abstract

Keywords

ASJC Scopus subject areas

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