Context is key: Modulated protein multivalency in disease

Mikayla Eppert, Benjamin R. Sabari

Research output: Contribution to journalComment/debatepeer-review


In this issue of Molecular Cell, Song et al. demonstrate that mutations to the YEATS domain of ENL aberrantly activate gene expression by forming condensates on specific genomic loci. By using diverse experimental approaches, the authors dissect the molecular underpinnings of ENL mutant condensate formation.

Original languageEnglish (US)
Pages (from-to)3965-3967
Number of pages3
JournalMolecular cell
Issue number21
StatePublished - Nov 3 2022

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology


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