Abstract
Inert gas isotopes are finding more commonplace use in the measurement of blood perfusion in the capillary beds of patients who have experienced the symptoms of a myocardial infarction. This study analyzes the effects on the calculated perfusion rate of various techniques for collecting and displaying clearance curves following a bolus injection of the inert gas isotope into the left coronary artery of the dog. The study is motivated by the need to maximize the sampling period (data collection time for one point on the clearance curve), minimize the observation time (total length of the clearance curve) and to maximize the spatial sampling interval (size of the regional area selected for investigation). The resulting procedure minimizes patient exposure to radiation, since smaller isotope dosage is required to produce statistically significant clearance curves. In addition, bulk storage costs are minimized by eliminating the storage of unnecessary data.
Original language | English (US) |
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Title of host publication | Unknown Host Publication Title |
Place of Publication | Calif |
Publisher | San Diego Biomed Symp (v 12) |
Pages | 237-240 |
Number of pages | 4 |
State | Published - 1973 |
Event | San Diego Biomed Symp, Proc - San Diego, CA, USA Duration: Jan 31 1973 → Feb 2 1973 |
Other
Other | San Diego Biomed Symp, Proc |
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City | San Diego, CA, USA |
Period | 1/31/73 → 2/2/73 |
ASJC Scopus subject areas
- Engineering(all)