Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus

Dedee F. Murrell; Sarah Dick; A. R. Ahmed; Masayuki Amagai; Maria A. Barnadas; Luca Borradori; Jean Claude Bystryn; Giuseppe Cianchini; Luis Diaz; David Fivenson; Russell Hall; Karen E. Harman; Takashi Hashimoto; Michael Hertl; Nico Hunzelmann; Pilar Iranzo; Pascal Joly; Marcel F. Jonkman; Yasuo Kitajima; Neil J. Korman; Linda K. Martin; Daniel Mimouni; Amit G. Pandya; Aimee S. Payne; David Rubenstein; Hiroshi Shimizu; Animesh A. Sinha; David Sirois; Detlef Zillikens; Victoria P. Werth

doi:10.1016/j.jaad.2008.01.012

Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus

Dedee F. Murrell, Sarah Dick, A. R. Ahmed, Masayuki Amagai, Maria A. Barnadas, Luca Borradori, Jean Claude Bystryn, Giuseppe Cianchini, Luis Diaz, David Fivenson, Russell Hall, Karen E. Harman, Takashi Hashimoto, Michael Hertl, Nico Hunzelmann, Pilar Iranzo, Pascal Joly, Marcel F. Jonkman, Yasuo Kitajima, Neil J. KormanLinda K. Martin, Daniel Mimouni, Amit G. Pandya, Aimee S. Payne, David Rubenstein, Hiroshi Shimizu, Animesh A. Sinha, David Sirois, Detlef Zillikens, Victoria P. Werth

Research output: Contribution to journal › Review article › peer-review

451 Scopus citations

Abstract

Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.

Original language	English (US)
Pages (from-to)	1043-1046
Number of pages	4
Journal	Journal of the American Academy of Dermatology
Volume	58
Issue number	6
DOIs	https://doi.org/10.1016/j.jaad.2008.01.012
State	Published - Jun 2008

ASJC Scopus subject areas

Dermatology

Access to Document

10.1016/j.jaad.2008.01.012

Cite this

Murrell, D. F., Dick, S., Ahmed, A. R., Amagai, M., Barnadas, M. A., Borradori, L., Bystryn, J. C., Cianchini, G., Diaz, L., Fivenson, D., Hall, R., Harman, K. E., Hashimoto, T., Hertl, M., Hunzelmann, N., Iranzo, P., Joly, P., Jonkman, M. F., Kitajima, Y., ... Werth, V. P. (2008). Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus. Journal of the American Academy of Dermatology, 58(6), 1043-1046. https://doi.org/10.1016/j.jaad.2008.01.012

Murrell, DF, Dick, S, Ahmed, AR, Amagai, M, Barnadas, MA, Borradori, L, Bystryn, JC, Cianchini, G, Diaz, L, Fivenson, D, Hall, R, Harman, KE, Hashimoto, T, Hertl, M, Hunzelmann, N, Iranzo, P, Joly, P, Jonkman, MF, Kitajima, Y, Korman, NJ, Martin, LK, Mimouni, D, Pandya, AG, Payne, AS, Rubenstein, D, Shimizu, H, Sinha, AA, Sirois, D, Zillikens, D & Werth, VP 2008, 'Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus', Journal of the American Academy of Dermatology, vol. 58, no. 6, pp. 1043-1046. https://doi.org/10.1016/j.jaad.2008.01.012

@article{e2c20786381741c9854521021e8217b3,

title = "Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus",

abstract = "Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.",

author = "Murrell, {Dedee F.} and Sarah Dick and Ahmed, {A. R.} and Masayuki Amagai and Barnadas, {Maria A.} and Luca Borradori and Bystryn, {Jean Claude} and Giuseppe Cianchini and Luis Diaz and David Fivenson and Russell Hall and Harman, {Karen E.} and Takashi Hashimoto and Michael Hertl and Nico Hunzelmann and Pilar Iranzo and Pascal Joly and Jonkman, {Marcel F.} and Yasuo Kitajima and Korman, {Neil J.} and Martin, {Linda K.} and Daniel Mimouni and Pandya, {Amit G.} and Payne, {Aimee S.} and David Rubenstein and Hiroshi Shimizu and Sinha, {Animesh A.} and David Sirois and Detlef Zillikens and Werth, {Victoria P.}",

year = "2008",

month = jun,

doi = "10.1016/j.jaad.2008.01.012",

language = "English (US)",

volume = "58",

pages = "1043--1046",

journal = "Journal of the American Academy of Dermatology",

issn = "0190-9622",

publisher = "Mosby Inc.",

number = "6",

}

TY - JOUR

T1 - Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus

AU - Murrell, Dedee F.

AU - Dick, Sarah

AU - Ahmed, A. R.

AU - Amagai, Masayuki

AU - Barnadas, Maria A.

AU - Borradori, Luca

AU - Bystryn, Jean Claude

AU - Cianchini, Giuseppe

AU - Diaz, Luis

AU - Fivenson, David

AU - Hall, Russell

AU - Harman, Karen E.

AU - Hashimoto, Takashi

AU - Hertl, Michael

AU - Hunzelmann, Nico

AU - Iranzo, Pilar

AU - Joly, Pascal

AU - Jonkman, Marcel F.

AU - Kitajima, Yasuo

AU - Korman, Neil J.

AU - Martin, Linda K.

AU - Mimouni, Daniel

AU - Pandya, Amit G.

AU - Payne, Aimee S.

AU - Rubenstein, David

AU - Shimizu, Hiroshi

AU - Sinha, Animesh A.

AU - Sirois, David

AU - Zillikens, Detlef

AU - Werth, Victoria P.

PY - 2008/6

Y1 - 2008/6

N2 - Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.

AB - Our scientific knowledge of pemphigus has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in pemphigus. A major obstacle in comparing therapeutic outcomes between centers is the lack of generally accepted definitions and measurements for the clinical evaluation of patients with pemphigus. Common terms and end points of pemphigus are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. This consensus statement from the International Pemphigus Committee represents 2 years of collaborative efforts to attain mutually acceptable common definitions for pemphigus. These should assist in development of consistent reporting of outcomes in future studies.

UR - http://www.scopus.com/inward/record.url?scp=43449130884&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43449130884&partnerID=8YFLogxK

U2 - 10.1016/j.jaad.2008.01.012

DO - 10.1016/j.jaad.2008.01.012

M3 - Review article

C2 - 18339444

AN - SCOPUS:43449130884

SN - 0190-9622

VL - 58

SP - 1043

EP - 1046

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

IS - 6

ER -

Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this