Conformation model of excitable cell membranes. III. Electric stimulation (Russian)

Y. A. Chizmadzhev, V. S. Markin, A. L. Muler, I. P. Zdorov

Research output: Contribution to journalArticlepeer-review


Calculation was made of sodium and potassium currents passing through an excitable membrane with a fixed membrane potential. It was shown that the stable potassium current can have a region with negative resistance over the hyperpolarization area. Behavior of membrane potential and fractions of conducting sodium and potassium channels during the generation of the action potential were found by numerical methods. The effect of various parameters on the behavior and form of the spike was studied. It was shown that the membrane model described enables many dynamic characters to be described, particularly the phenomenon of sharp depolarization.

Original languageEnglish (US)
Pages (from-to)674-680
Number of pages7
Issue number4
StatePublished - Jan 1 1973

ASJC Scopus subject areas

  • Medicine(all)


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