Computation-guided development of Au-catalyzed cycloisomerizations proceeding via 1,2-Si or 1,2-H migrations: Regiodivergent synthesis of silylfurans

Chemical Compounds

• Alkyl Group 12%
• Aryl Group 14%
• Carbene 12%
• Chemical Transformation 16%
• Counterion 23%
• Cyclization Reaction 19%
• Cycloisomerization 68%
• Density Functional Theory 32%
• Dissociation 9%
• H Group 17%
• Isomerization 10%
• Ligand 5%
• Polar Solvent 13%
• Regioselectivity 12%
• Solvation 11%
• Solvent 6%
• Solvent Effect 25%
• Triflate 13%

Medicine & Life Sciences

• carbene 100%
• Cyclization 26%
• Density Functional Theory 61%
• Ketones 22%
• Ligands 6%

Engineering & Materials Science

• Cyclization 30%
• Discrete Fourier transforms 57%
• Isomerization 12%
• Ketones 25%
• Ligands 11%
• Protonation 16%
• Regioselectivity 18%
• Solvation 13%