Comparison of spet brain perfusion and 18f-fdg brain metabolism in patients with chronic fatigue syndrome

H. H. Abu-Judeh; S. Levine; M. Kumar; H. El-Zeftawy; S. Naddaf; J. Q. Lou; H. M. Abdel-Dayem

doi:10.1080/00006231-199811000-00006

Comparison of spet brain perfusion and ¹⁸f-fdg brain metabolism in patients with chronic fatigue syndrome

H. H. Abu-Judeh, S. Levine, M. Kumar, H. El-Zeftawy, S. Naddaf, J. Q. Lou, H. M. Abdel-Dayem

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Chrome fatigue syndrome is a clinically defined condition of uncertain aetiology. We compared ⁹⁹Tc^m-HMPAO single photon emission tomography (SPET) brain perfusion with dual-head ¹⁸F-FDG brain metabolism in patients with chronic fatigue syndrome. Eighteen patients (14 females, 4 males), who fulfilled the diagnostic criteria of the Centers for Disease Control for chronic fatigue syndrome, were investigated. Thirteen patients had abnormal SPET brain perfusion scans and five had normal scans. Fifteen patients had normal glucose brain metabolism scans and three had abnormal scans. We conclude that, in chronic fatigue syndrome patients, there is discordance between SPET brain perfusion and ¹⁸F-FDG brain uptake. It is possible to have brain perfusion abnormalities without corresponding changes in glucose uptake. (

Original language	English (US)
Pages (from-to)	1065-1072
Number of pages	8
Journal	Nuclear Medicine Communications
Volume	19
Issue number	11
DOIs	https://doi.org/10.1080/00006231-199811000-00006
State	Published - Nov 1998

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1080/00006231-199811000-00006

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title = "Comparison of spet brain perfusion and 18f-fdg brain metabolism in patients with chronic fatigue syndrome",

abstract = "Chrome fatigue syndrome is a clinically defined condition of uncertain aetiology. We compared 99Tcm-HMPAO single photon emission tomography (SPET) brain perfusion with dual-head 18F-FDG brain metabolism in patients with chronic fatigue syndrome. Eighteen patients (14 females, 4 males), who fulfilled the diagnostic criteria of the Centers for Disease Control for chronic fatigue syndrome, were investigated. Thirteen patients had abnormal SPET brain perfusion scans and five had normal scans. Fifteen patients had normal glucose brain metabolism scans and three had abnormal scans. We conclude that, in chronic fatigue syndrome patients, there is discordance between SPET brain perfusion and 18F-FDG brain uptake. It is possible to have brain perfusion abnormalities without corresponding changes in glucose uptake. (",

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AU - Abu-Judeh, H. H.

AU - Levine, S.

AU - Kumar, M.

AU - El-Zeftawy, H.

AU - Naddaf, S.

AU - Lou, J. Q.

AU - Abdel-Dayem, H. M.

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N2 - Chrome fatigue syndrome is a clinically defined condition of uncertain aetiology. We compared 99Tcm-HMPAO single photon emission tomography (SPET) brain perfusion with dual-head 18F-FDG brain metabolism in patients with chronic fatigue syndrome. Eighteen patients (14 females, 4 males), who fulfilled the diagnostic criteria of the Centers for Disease Control for chronic fatigue syndrome, were investigated. Thirteen patients had abnormal SPET brain perfusion scans and five had normal scans. Fifteen patients had normal glucose brain metabolism scans and three had abnormal scans. We conclude that, in chronic fatigue syndrome patients, there is discordance between SPET brain perfusion and 18F-FDG brain uptake. It is possible to have brain perfusion abnormalities without corresponding changes in glucose uptake. (

AB - Chrome fatigue syndrome is a clinically defined condition of uncertain aetiology. We compared 99Tcm-HMPAO single photon emission tomography (SPET) brain perfusion with dual-head 18F-FDG brain metabolism in patients with chronic fatigue syndrome. Eighteen patients (14 females, 4 males), who fulfilled the diagnostic criteria of the Centers for Disease Control for chronic fatigue syndrome, were investigated. Thirteen patients had abnormal SPET brain perfusion scans and five had normal scans. Fifteen patients had normal glucose brain metabolism scans and three had abnormal scans. We conclude that, in chronic fatigue syndrome patients, there is discordance between SPET brain perfusion and 18F-FDG brain uptake. It is possible to have brain perfusion abnormalities without corresponding changes in glucose uptake. (

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Comparison of spet brain perfusion and ¹⁸f-fdg brain metabolism in patients with chronic fatigue syndrome

Abstract

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