Comparison of ginsenosides in radix and rhizome of wild Panax species using LC-ELSD and LC-Q-TOF-MS

Nozimakhonim Yunusova, Jae Young Kim, Gwang Jin Lee, Ji Yeon Hong, Byong kyu Shin, Shao Qing Cai, Xiang Lan Piao, Jeong Hill Park, Sung Won Kwon

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


High-performance liquid chromatography (HPLC) with evaporative light scattering detector (ELSD) and quadrupole time-of-flight mass spectrometry (Q-TOF-MS) were used for qualitative and quantitative analysis of wild Panax species, especially wild P. vietnamensis, which is an important medicinal plant. We determined the types and concentrations of ginsenosides in radix and rhizome of wild P. vietnamensis. Identification of ginsenosides was achieved using Q-TOF-MS; concentrations were determined by ELSD. The most abundant ginsenosides in wild Vietnamese ginseng were of the ocotillol type, accounting for more than 50% of the total. Compared to the rhizome, the radix had 31% higher ginsenoside content due to variation in protopanaxatriol-type ginsenoside contents. We also found an unusual difference in the chromatograms of the two parts of wild P. vietnamensis. This difference did not appear in other wild species such as P. ginseng and P. quinquefolius. Our study provides an opportunity for further in-depth study of the distinctive characteristics of P. vietnamensis.

Original languageEnglish (US)
Pages (from-to)1607-1614
Number of pages8
JournalInternational Journal of Food Science and Technology
Issue number7
StatePublished - Jul 1 2015


  • Chemical composition
  • Ginsenosides
  • High-performance liquid chromatography

ASJC Scopus subject areas

  • Food Science
  • Industrial and Manufacturing Engineering


Dive into the research topics of 'Comparison of ginsenosides in radix and rhizome of wild Panax species using LC-ELSD and LC-Q-TOF-MS'. Together they form a unique fingerprint.

Cite this