Common Solid Tumors of Childhood

William M. Crist, Larry E. Kun

Research output: Contribution to journalReview articlepeer-review

194 Scopus citations

Abstract

CHILDHOOD cancer is rare in the United States, but it is the leading cause of death from disease in children 1 to 15 years old.1 The majority of cancers in children are malignant solid tumors, and about 4000 new cases are diagnosed each year.1 Enormous strides have been made in the management of these neoplasms since Farber first demonstrated the sensitivity of metastatic Wilms' tumor to dactinomycin in the mid-1960s.2 For example, rates of cure for solid tumors have increased by as much as 50 percent; new histologic subtypes with implications for prognosis have been identified and incorporated into systems.

Original languageEnglish (US)
Pages (from-to)461-471
Number of pages11
JournalNew England Journal of Medicine
Volume324
Issue number7
DOIs
StatePublished - Feb 14 1991

ASJC Scopus subject areas

  • General Medicine

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