Cold labile phosphofructokinase

Norio Kono, Kosaku Uyeda

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Phosphofructokinase from chicken liver undergoes reversible inactivation at low temperature. The rate of the inactivation increases with decrease in temperature. The cold inactivation is stimulated by monovalent anions or ATP, but prevented by polyvalent anions or fructose 1,6-di-P. Results of sucrose density gradient centrifugation indicate that the cold inactivation is associated with dissociation of the phosphofructokinase (13.9S) to a protein with a S value of 5.4.

Original languageEnglish (US)
Pages (from-to)1095-1100
Number of pages6
JournalBiochemical and Biophysical Research Communications
Issue number6
StatePublished - Mar 19 1971

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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