Cold cuts added to the circadian smorgasbord of regulatory mechanisms

Carla B. Green

doi:10.1101/gad.289587.116

Cold cuts added to the circadian smorgasbord of regulatory mechanisms

Carla B. Green

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In mammals, rhythms in body temperature help to entrain and synchronize circadian rhythms throughout the organism, and the cold-inducible RNA-binding protein (CIRBP) is one of the mediators of these daily temperature changes. CirbpmRNAexpression is regulated by the daily subtle rhythms in body temperature, and a new study by Gotic and colleagues (pp. 2005-2017) reveals a surprising and novel mechanism that involves temperature-dependent enhancement of splicing efficiency.

Original language	English (US)
Pages (from-to)	1909-1910
Number of pages	2
Journal	Genes and Development
Volume	30
Issue number	17
DOIs	https://doi.org/10.1101/gad.289587.116
State	Published - Sep 1 2016

Keywords

Cirbp
Circadian rhythms
Splicing efficiency
Temperature

ASJC Scopus subject areas

Genetics
Developmental Biology

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10.1101/gad.289587.116

Cite this

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abstract = "In mammals, rhythms in body temperature help to entrain and synchronize circadian rhythms throughout the organism, and the cold-inducible RNA-binding protein (CIRBP) is one of the mediators of these daily temperature changes. CirbpmRNAexpression is regulated by the daily subtle rhythms in body temperature, and a new study by Gotic and colleagues (pp. 2005-2017) reveals a surprising and novel mechanism that involves temperature-dependent enhancement of splicing efficiency.",

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AB - In mammals, rhythms in body temperature help to entrain and synchronize circadian rhythms throughout the organism, and the cold-inducible RNA-binding protein (CIRBP) is one of the mediators of these daily temperature changes. CirbpmRNAexpression is regulated by the daily subtle rhythms in body temperature, and a new study by Gotic and colleagues (pp. 2005-2017) reveals a surprising and novel mechanism that involves temperature-dependent enhancement of splicing efficiency.

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KW - Splicing efficiency

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Cold cuts added to the circadian smorgasbord of regulatory mechanisms

Abstract

Keywords

ASJC Scopus subject areas

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