Cold cuts added to the circadian smorgasbord of regulatory mechanisms

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1 Scopus citations


In mammals, rhythms in body temperature help to entrain and synchronize circadian rhythms throughout the organism, and the cold-inducible RNA-binding protein (CIRBP) is one of the mediators of these daily temperature changes. CirbpmRNAexpression is regulated by the daily subtle rhythms in body temperature, and a new study by Gotic and colleagues (pp. 2005-2017) reveals a surprising and novel mechanism that involves temperature-dependent enhancement of splicing efficiency.

Original languageEnglish (US)
Pages (from-to)1909-1910
Number of pages2
JournalGenes and Development
Issue number17
StatePublished - Sep 1 2016


  • Cirbp
  • Circadian rhythms
  • Splicing efficiency
  • Temperature

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology


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