Clinico-pathologic disparities of breast cancer in Hispanic/Latina women

Z. Nahleh, G. Botrus, A. Dwivedi, N. Badri, S. Otoukesh, N. Diab, S. Biswas, M. Jennings, S. Elzamly

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


BACKGROUND: Breast cancer is the leading cause of cancer death in Hispanic/Latina women nationwide. Limited cancer research has been conducted in this population. El Paso, Texas is a large border city with a population of around 900,000, of which 85% are Latinos and would provide a suitable setting for this study. The aim of this study is to evaluate ethnic differences and cancer characteristics in Hispanic/latina women with breast cancer. METHODS: After IRB approval, we retrospectively analyzed the variables of patients with breast cancer treated consecutively at a large tertiary medical center in El Paso, TX between 2005-2015. Descriptive statistics, bivariate, and multivariable analyses were conducted. RESULTS: 1,252 patients were identified. Mean age at diagnosis was 57 years. 1074 were Hispanics/Latinas (86%). When comparing Hispanics versus non-Hispanics, 31% of Hispanics compared to 24% Non-Hispanics were diagnosed at age <50 (P = 0:043). More Hispanics are uninsured (34%) compared to Non-Hispanics (25%) (p = 0:008). Hispanics presenting with advanced stages were more likely to be uninsured (P = 0:02). CONCLUSIONS: This analysis confirms that Hispanics/Latinas are diagnosed with breast cancer at a younger age and are more commonly uninsured than Non-Hispanics. We did not observe significant differences in the prevalence of ER+, triple negative or Her2 -neu positive disease or stages at presentation between the 2 groups in this cohort, however the non-Hispanic group was constituted only 14% of the studied population. A larger multi-institutional comparative study is being conducted to confirm these findings.

Original languageEnglish (US)
Pages (from-to)147-154
Number of pages8
JournalBreast Disease
Issue number3
StatePublished - 2018
Externally publishedYes


  • breast
  • cancer
  • ethnic
  • Hispanic

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


Dive into the research topics of 'Clinico-pathologic disparities of breast cancer in Hispanic/Latina women'. Together they form a unique fingerprint.

Cite this