Clinical and genetic evidence that juvenile arthritis is not a single disease

C. W. Fink; M. Fernandez-Vina; P. Stastny

doi:10.1016/S0031-3955(16)40057-X

Clinical and genetic evidence that juvenile arthritis is not a single disease

C. W. Fink, M. Fernandez-Vina, P. Stastny

Internal Medicine

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Ample evidence shows that what was formerly called 'juvenile rheumatoid arthritis' is not a single disease. At least six separate diseases were included as subgroups or subtypes of juvenile rheumatoid arthritis in other classifications. The clinical and laboratory features that differentiate these diseases are discussed. Genetic differences, primarily within the HLA system but also for T-cell receptor genes are described and correlated with the new clinical classification of arthritis.

Original language	English (US)
Pages (from-to)	1155-1169
Number of pages	15
Journal	Pediatric clinics of North America
Volume	42
Issue number	5
DOIs	https://doi.org/10.1016/S0031-3955(16)40057-X
State	Published - 1995

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0031-3955(16)40057-X

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title = "Clinical and genetic evidence that juvenile arthritis is not a single disease",

abstract = "Ample evidence shows that what was formerly called 'juvenile rheumatoid arthritis' is not a single disease. At least six separate diseases were included as subgroups or subtypes of juvenile rheumatoid arthritis in other classifications. The clinical and laboratory features that differentiate these diseases are discussed. Genetic differences, primarily within the HLA system but also for T-cell receptor genes are described and correlated with the new clinical classification of arthritis.",

author = "Fink, {C. W.} and M. Fernandez-Vina and P. Stastny",

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AU - Fink, C. W.

AU - Fernandez-Vina, M.

AU - Stastny, P.

PY - 1995

Y1 - 1995

N2 - Ample evidence shows that what was formerly called 'juvenile rheumatoid arthritis' is not a single disease. At least six separate diseases were included as subgroups or subtypes of juvenile rheumatoid arthritis in other classifications. The clinical and laboratory features that differentiate these diseases are discussed. Genetic differences, primarily within the HLA system but also for T-cell receptor genes are described and correlated with the new clinical classification of arthritis.

AB - Ample evidence shows that what was formerly called 'juvenile rheumatoid arthritis' is not a single disease. At least six separate diseases were included as subgroups or subtypes of juvenile rheumatoid arthritis in other classifications. The clinical and laboratory features that differentiate these diseases are discussed. Genetic differences, primarily within the HLA system but also for T-cell receptor genes are described and correlated with the new clinical classification of arthritis.

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U2 - 10.1016/S0031-3955(16)40057-X

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JO - Pediatric clinics of North America

JF - Pediatric clinics of North America

IS - 5

ER -

Clinical and genetic evidence that juvenile arthritis is not a single disease

Abstract

ASJC Scopus subject areas

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