@article{6015918b43f0432b92b7eab3ec8d1ee9,
title = "CLASPs at a glance",
abstract = "CLIP-associating proteins (CLASPs) form an evolutionarily conserved family of regulatory factors that control microtubule dynamics and the organization of microtubule networks. The importance of CLASP activity has been appreciated for some time, but until recently our understanding of the underlying molecular mechanisms remained basic. Over the past few years, studies of, for example, migrating cells, neuronal development, and microtubule reorganization in plants, along with in vitro reconstitutions, have provided new insights into the cellular roles and molecular basis of CLASP activity. In this Cell Science at a Glance article and the accompanying poster, we will summarize some of these recent advances, emphasizing how they impact our current understanding of CLASP-mediated microtubule regulation.",
keywords = "CLASP, Microtubule dynamics, Mitosis, Motility",
author = "Lawrence, {Elizabeth J.} and Marija Zanic and Rice, {Luke M.}",
note = "Funding Information: E.J.L. acknowledges the support of the National Institutes of Health IBSTO training grant T32CA119925. M.Z. acknowledges support from the National Institutes of Health grant R35GM119552, and the Searle Scholars Program. Work on TOG domain proteins in L.M.R.'s lab has been supported by grants from the National Institutes of Health (R01-GM098543) and from the Robert A. Welch Foundation (I-1908). Deposited in PMC for release after 12 months. Funding Information: E.J.L. acknowledges the support of the National Institutes of Health IBSTO training grant T32CA119925. M.Z. acknowledges support from the National Institutes of Health grant R35GM119552, and the Searle Scholars Program. Work on TOG domain proteins in L.M.R.{\textquoteright}s lab has been supported by grants from the National Institutes of Health (R01-GM098543) and from the Robert A. Welch Foundation (I-1908). Deposited in PMC for release after 12 months. Publisher Copyright: {\textcopyright} 2020 Published by The Company of Biologists Ltd.",
year = "2020",
month = apr,
doi = "10.1242/jcs.243097",
language = "English (US)",
volume = "133",
journal = "The Quarterly journal of microscopical science",
issn = "0021-9533",
publisher = "Company of Biologists Ltd",
number = "8",
}