TY - JOUR
T1 - Circadian rhythms in infectious diseases and symbiosis
AU - Rijo-Ferreira, Filipa
AU - Takahashi, Joseph S.
N1 - Funding Information:
We thank Fernando Augusto (made-for.studio) for the design of the figures and Kimberly Cox (Efferent Manuscript Services). Apologies to those whose work was not cited because of content and length constraints. This work was supported by the Howard Hughes Medical Institute and National Institutes of Health, National Institute of General Medical Sciences, USA, 1K99GM132557 (F.R.-F.). J.S.T. is an Investigator in the Howard Hughes Medical Institute. The authors declare no competing interest.
Funding Information:
We thank Fernando Augusto (made-for.studio) for the design of the figures and Kimberly Cox (Efferent Manuscript Services). Apologies to those whose work was not cited because of content and length constraints. This work was supported by the Howard Hughes Medical Institute and National Institutes of Health, National Institute of General Medical Sciences, USA , 1K99GM132557 (F.R.-F.). J.S.T. is an Investigator in the Howard Hughes Medical Institute.
Publisher Copyright:
© 2021
PY - 2022/6
Y1 - 2022/6
N2 - Timing is everything. Many organisms across the tree of life have evolved timekeeping mechanisms that regulate numerous of their cellular functions to optimize timing by anticipating changes in the environment. The specific environmental changes that are sensed depends on the organism. For animals, plants, and free-living microbes, environmental cues include light/dark cycles, daily temperature fluctuations, among others. In contrast, for a microbe that is never free-living, its rhythmic environment is its host's rhythmic biology. Here, we describe recent research on the interactions between hosts and microbes, from the perspective both of symbiosis as well as infections. In addition to describing the biology of the microbes, we focus specifically on how circadian clocks modulate these host-microbe interactions.
AB - Timing is everything. Many organisms across the tree of life have evolved timekeeping mechanisms that regulate numerous of their cellular functions to optimize timing by anticipating changes in the environment. The specific environmental changes that are sensed depends on the organism. For animals, plants, and free-living microbes, environmental cues include light/dark cycles, daily temperature fluctuations, among others. In contrast, for a microbe that is never free-living, its rhythmic environment is its host's rhythmic biology. Here, we describe recent research on the interactions between hosts and microbes, from the perspective both of symbiosis as well as infections. In addition to describing the biology of the microbes, we focus specifically on how circadian clocks modulate these host-microbe interactions.
KW - Bacteria
KW - Circadian rhythms
KW - Host
KW - Infectious diseases
KW - Parasite
KW - Symbiosis
KW - Virus
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U2 - 10.1016/j.semcdb.2021.09.004
DO - 10.1016/j.semcdb.2021.09.004
M3 - Review article
C2 - 34625370
AN - SCOPUS:85116664429
SN - 1084-9521
VL - 126
SP - 37
EP - 44
JO - Seminars in Cell and Developmental Biology
JF - Seminars in Cell and Developmental Biology
ER -