TY - JOUR
T1 - Chronic Thromboembolic Pulmonary Hypertension in a Patient Heterozygous for both Factor V Leiden and the G20210A Prothrombin Mutation
AU - Kourgiannidis, George K.
AU - Brilakis, Emmanuel S.
AU - Manginas, Athanasios N.
AU - Cokkinos, Dennis V.
PY - 2003/5/1
Y1 - 2003/5/1
N2 - Coagulation abnormalities have been implicated in the pathogenesis of chronic thromboembolic pulmonary hypertension, a serious disease with poor prognosis. We describe the first case of a 32-year-old heterozygous carrier of both factor V Leiden and the G20210A prothrombin mutation who developed severe chronic thromboembolic pulmonary hypertension, and was subsequently managed successfully with pulmonary thrombarterectomy.
AB - Coagulation abnormalities have been implicated in the pathogenesis of chronic thromboembolic pulmonary hypertension, a serious disease with poor prognosis. We describe the first case of a 32-year-old heterozygous carrier of both factor V Leiden and the G20210A prothrombin mutation who developed severe chronic thromboembolic pulmonary hypertension, and was subsequently managed successfully with pulmonary thrombarterectomy.
KW - Chronic pulmonary embolism
KW - Factor V Leiden
KW - Prothrombin mutation G20210A
KW - Pulmonary hypertension
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M3 - Article
AN - SCOPUS:0842269028
SN - 1011-7970
VL - 44
SP - 218
EP - 221
JO - Hellenic Journal of Cardiology
JF - Hellenic Journal of Cardiology
IS - 3
ER -