Abstract
Chromosome segregation requires the removal of cohesion and catenation between sister chromosomes, two physical linkages established during DNA replication. Two new studies reveal that, among other functions, the wings apart-like protein (Wapl) coordinates cohesin removal with decatenation of sister chromosomes during mitosis in mammalian cells.
Original language | English (US) |
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Pages (from-to) | R923-R925 |
Journal | Current Biology |
Volume | 23 |
Issue number | 20 |
DOIs | |
State | Published - Oct 21 2013 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Agricultural and Biological Sciences(all)