Chiral allene-containing phosphines in asymmetric catalysis

Feng Cai, Xiaotao Pu, Xiangbing Qi, Vincent Lynch, Akella Radha, Joseph M. Ready

Research output: Contribution to journalArticlepeer-review

110 Scopus citations


We demonstrate that allenes, chiral 1,2-dienes, appended with basic functionality can serve as ligands for transition metals. We describe an allene-containing bisphosphine that, when coordinated to Rh(I), promotes the asymmetric addition of arylboronic acids to α-keto esters with high enantioselectivity. Solution and solid-state structural analysis reveals that one olefin of the allene can coordinate to transition metals, generating bi- and tridentate ligands.

Original languageEnglish (US)
Pages (from-to)18066-18069
Number of pages4
JournalJournal of the American Chemical Society
Issue number45
StatePublished - Nov 16 2011

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry


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