Chemistry for DOTA peptide labeling at phenylalanine residues: On the road to preparing peptide ligand tagged libraries

Luis M. De León-Rodríguez; Zoltan Kovacs; Alan D. Sherry

doi:10.2174/1570178053202838

Chemistry for DOTA peptide labeling at phenylalanine residues: On the road to preparing peptide ligand tagged libraries

Luis M. De León-Rodríguez, Zoltan Kovacs, Alan D. Sherry

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Different synthetic strategies to control the position of DOTA in phenylalanine residues within a peptide sequence were studied and compared. The results showed that use of DOTA pre-labeled amino acids stands as the most promising procedure for the synthesis of peptide ligand tagged libraries by solid phase peptide synthesis.

Original language	English (US)
Pages (from-to)	160-164
Number of pages	5
Journal	Letters in Organic Chemistry
Volume	2
Issue number	2
DOIs	https://doi.org/10.2174/1570178053202838
State	Published - Mar 2005

Keywords

DOTA
MRI
Peptide
Phenylalanine
Tag

ASJC Scopus subject areas

Biochemistry
Organic Chemistry

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10.2174/1570178053202838

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title = "Chemistry for DOTA peptide labeling at phenylalanine residues: On the road to preparing peptide ligand tagged libraries",

abstract = "Different synthetic strategies to control the position of DOTA in phenylalanine residues within a peptide sequence were studied and compared. The results showed that use of DOTA pre-labeled amino acids stands as the most promising procedure for the synthesis of peptide ligand tagged libraries by solid phase peptide synthesis.",

keywords = "DOTA, MRI, Peptide, Phenylalanine, Tag",

author = "{De Le{\'o}n-Rodr{\'i}guez}, {Luis M.} and Zoltan Kovacs and Sherry, {Alan D.}",

year = "2005",

month = mar,

doi = "10.2174/1570178053202838",

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T1 - Chemistry for DOTA peptide labeling at phenylalanine residues

T2 - On the road to preparing peptide ligand tagged libraries

AU - De León-Rodríguez, Luis M.

AU - Kovacs, Zoltan

AU - Sherry, Alan D.

PY - 2005/3

Y1 - 2005/3

N2 - Different synthetic strategies to control the position of DOTA in phenylalanine residues within a peptide sequence were studied and compared. The results showed that use of DOTA pre-labeled amino acids stands as the most promising procedure for the synthesis of peptide ligand tagged libraries by solid phase peptide synthesis.

AB - Different synthetic strategies to control the position of DOTA in phenylalanine residues within a peptide sequence were studied and compared. The results showed that use of DOTA pre-labeled amino acids stands as the most promising procedure for the synthesis of peptide ligand tagged libraries by solid phase peptide synthesis.

KW - DOTA

KW - MRI

KW - Peptide

KW - Phenylalanine

KW - Tag

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M3 - Review article

AN - SCOPUS:35648999991

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JO - Letters in Organic Chemistry

JF - Letters in Organic Chemistry

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Chemistry for DOTA peptide labeling at phenylalanine residues: On the road to preparing peptide ligand tagged libraries

Abstract

Keywords

ASJC Scopus subject areas

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