Abstract
Different synthetic strategies to control the position of DOTA in phenylalanine residues within a peptide sequence were studied and compared. The results showed that use of DOTA pre-labeled amino acids stands as the most promising procedure for the synthesis of peptide ligand tagged libraries by solid phase peptide synthesis.
Original language | English (US) |
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Pages (from-to) | 160-164 |
Number of pages | 5 |
Journal | Letters in Organic Chemistry |
Volume | 2 |
Issue number | 2 |
DOIs | |
State | Published - Mar 2005 |
Keywords
- DOTA
- MRI
- Peptide
- Phenylalanine
- Tag
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry