TY - JOUR
T1 - Changes in hepatic lipids of mice infected with cysticerci of Taenia crassiceps
AU - Corbin, I.
AU - Novak, M.
AU - Blackburn, B. J.
N1 - Funding Information:
The financial assistance of NSERC (a grant to MN and BJB) is gratefully acknowledged. We thank T. Durham and T. Wolowiec for excellent technical assistance.
PY - 2000
Y1 - 2000
N2 - Nuclear magnetic resonance (NMR) spectroscopy was employed to investigate the effect of infection with Taenia crassiceps cysticerci on the lipid profile of mouse liver. Chloroform/methanol extracts of livers from infected mice showed lower concentrations of phosphatidylethanolamine, phosphatidylcholine, phosphatidylinositol, total glycerophospholipid, triacylglycerol, total fatty acid (FA) and all measured FA components than those from controls. Furthermore, the ratios obtained on dividing concentrations of the FA components by that of total FA demonstrate that the concentration decreases caused by infection are less for polyunsaturated fatty acids (FAs) than for other FAs. Extracts of T. crassiceps displayed a similar lipid profile to that of host liver but contained a lower lipid content and a shorter average FA chain length.
AB - Nuclear magnetic resonance (NMR) spectroscopy was employed to investigate the effect of infection with Taenia crassiceps cysticerci on the lipid profile of mouse liver. Chloroform/methanol extracts of livers from infected mice showed lower concentrations of phosphatidylethanolamine, phosphatidylcholine, phosphatidylinositol, total glycerophospholipid, triacylglycerol, total fatty acid (FA) and all measured FA components than those from controls. Furthermore, the ratios obtained on dividing concentrations of the FA components by that of total FA demonstrate that the concentration decreases caused by infection are less for polyunsaturated fatty acids (FAs) than for other FAs. Extracts of T. crassiceps displayed a similar lipid profile to that of host liver but contained a lower lipid content and a shorter average FA chain length.
UR - http://www.scopus.com/inward/record.url?scp=0033807855&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033807855&partnerID=8YFLogxK
U2 - 10.1017/s0022149x00000305
DO - 10.1017/s0022149x00000305
M3 - Article
C2 - 10953220
AN - SCOPUS:0033807855
SN - 0022-149X
VL - 74
SP - 209
EP - 214
JO - Journal of Helminthology
JF - Journal of Helminthology
IS - 3
ER -