TY - JOUR
T1 - Changes in Epidemiology of Acetaminophen Overdoses in an Urban County Hospital After 20 Years
AU - Long, Apple
AU - Magrath, Melissa
AU - Mihalopoulos, Meredith
AU - Rule, Jody A.
AU - Agrawal, Deepak
AU - Haley, Robert
AU - Kleinschmidt, Kurt
AU - Lee, William M.
N1 - Publisher Copyright:
© 2022 Wolters Kluwer Health. All rights reserved.
PY - 2022/8/1
Y1 - 2022/8/1
N2 - INTRODUCTION:Acetaminophen (APAP) toxicity is the main cause of acute liver failure in the United States. A prior series (1992-1995) identified 71 hospitalized adults with APAP toxicity through the International Statistical Classification of Disease and Related Health Problems, 9th revision (ICD-9) code at Parkland Hospital, Dallas, TX.METHODS:We used a laboratory database search of serum APAP levels from 2011 to 2015 to identify patients with APAP toxicity in the same hospital.RESULTS:We identified 140 patients hospitalized for APAP toxicity from 27,143 APAP levels obtained; 35 required Intensive Care Unit (ICU) admission, and there were no deaths. APAP toxicity/100,000 admissions was similar between eras.DISCUSSION:APAP toxicity continues unabated after 20 years but with improved overall outcomes.
AB - INTRODUCTION:Acetaminophen (APAP) toxicity is the main cause of acute liver failure in the United States. A prior series (1992-1995) identified 71 hospitalized adults with APAP toxicity through the International Statistical Classification of Disease and Related Health Problems, 9th revision (ICD-9) code at Parkland Hospital, Dallas, TX.METHODS:We used a laboratory database search of serum APAP levels from 2011 to 2015 to identify patients with APAP toxicity in the same hospital.RESULTS:We identified 140 patients hospitalized for APAP toxicity from 27,143 APAP levels obtained; 35 required Intensive Care Unit (ICU) admission, and there were no deaths. APAP toxicity/100,000 admissions was similar between eras.DISCUSSION:APAP toxicity continues unabated after 20 years but with improved overall outcomes.
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U2 - 10.14309/ajg.0000000000001826
DO - 10.14309/ajg.0000000000001826
M3 - Article
C2 - 35926495
AN - SCOPUS:85135424606
SN - 0002-9270
VL - 117
SP - 1324
EP - 1328
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 8
ER -