Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review

Andrés Coca-Pelaz; Leon Barnes; Alessandra Rinaldo; Antonio Cardesa; Jatin P. Shah; Juan P. Rodrigo; Carlos Suárez; Jean Anderson Eloy; Justin A. Bishop; Kenneth O. Devaney; Lester D.R. Thompson; Bruce M. Wenig; Primož Strojan; Marc Hamoir; Patrick J. Bradley; Douglas R. Gnepp; Carl E. Silver; Pieter J. Slootweg; Asterios Triantafyllou; Vincent Vander Poorten; Michelle D. Williams; Alena Skálová; Henrik Hellquist; Afshin Teymoortash; Jesus E. Medina; K. Thomas Robbins; Karen T. Pitman; Luiz P. Kowalski; Remco de Bree; William M. Mendenhall; Robert P. Takes; Alfio Ferlito

doi:10.1007/s12325-016-0311-z

Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review

Andrés Coca-Pelaz, Leon Barnes, Alessandra Rinaldo, Antonio Cardesa, Jatin P. Shah, Juan P. Rodrigo, Carlos Suárez, Jean Anderson Eloy, Justin A. Bishop, Kenneth O. Devaney, Lester D.R. Thompson, Bruce M. Wenig, Primož Strojan, Marc Hamoir, Patrick J. Bradley, Douglas R. Gnepp, Carl E. Silver, Pieter J. Slootweg, Asterios Triantafyllou, Vincent Vander PoortenMichelle D. Williams, Alena Skálová, Henrik Hellquist, Afshin Teymoortash, Jesus E. Medina, K. Thomas Robbins, Karen T. Pitman, Luiz P. Kowalski, Remco de Bree, William M. Mendenhall, Robert P. Takes, Alfio Ferlito

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to standardize a treatment protocol. One of the controversial points is the decision whether or not to perform an elective neck dissection on these patients. Because there is contradictory information about this issue, we have critically reviewed the literature from 1912 to 2015 on all reported cases of AdCC of the larynx in order to clarify this issue. During the most recent period of our review (1991–2015) with a more exact diagnosis of the tumor histology, 142 cases were observed of AdCC of the larynx, of which 91 patients had data pertaining to lymph node status. Eleven of the 91 patients (12.1%) had nodal metastasis and, based on this low proportion of patients, routine elective neck dissection is therefore not recommended.

Original language	English (US)
Pages (from-to)	553-579
Number of pages	27
Journal	Advances in Therapy
Volume	33
Issue number	4
DOIs	https://doi.org/10.1007/s12325-016-0311-z
State	Published - Apr 1 2016

Keywords

Adenoid cystic carcinoma
Clinical protocols
Elective neck dissection
Larynx
Lymph node metastasis
Neck
Oncology
Treatment

ASJC Scopus subject areas

Pharmacology (medical)

Access to Document

10.1007/s12325-016-0311-z

Cite this

Coca-Pelaz, A., Barnes, L., Rinaldo, A., Cardesa, A., Shah, J. P., Rodrigo, J. P., Suárez, C., Eloy, J. A., Bishop, J. A., Devaney, K. O., Thompson, L. D. R., Wenig, B. M., Strojan, P., Hamoir, M., Bradley, P. J., Gnepp, D. R., Silver, C. E., Slootweg, P. J., Triantafyllou, A., ... Ferlito, A. (2016). Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review. Advances in Therapy, 33(4), 553-579. https://doi.org/10.1007/s12325-016-0311-z

Coca-Pelaz, A, Barnes, L, Rinaldo, A, Cardesa, A, Shah, JP, Rodrigo, JP, Suárez, C, Eloy, JA, Bishop, JA, Devaney, KO, Thompson, LDR, Wenig, BM, Strojan, P, Hamoir, M, Bradley, PJ, Gnepp, DR, Silver, CE, Slootweg, PJ, Triantafyllou, A, Vander Poorten, V, Williams, MD, Skálová, A, Hellquist, H, Teymoortash, A, Medina, JE, Robbins, KT, Pitman, KT, Kowalski, LP, de Bree, R, Mendenhall, WM, Takes, RP & Ferlito, A 2016, 'Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review', Advances in Therapy, vol. 33, no. 4, pp. 553-579. https://doi.org/10.1007/s12325-016-0311-z

@article{8cc908309f8a44c187074c57a91db5be,

title = "Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review",

abstract = "Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to standardize a treatment protocol. One of the controversial points is the decision whether or not to perform an elective neck dissection on these patients. Because there is contradictory information about this issue, we have critically reviewed the literature from 1912 to 2015 on all reported cases of AdCC of the larynx in order to clarify this issue. During the most recent period of our review (1991–2015) with a more exact diagnosis of the tumor histology, 142 cases were observed of AdCC of the larynx, of which 91 patients had data pertaining to lymph node status. Eleven of the 91 patients (12.1%) had nodal metastasis and, based on this low proportion of patients, routine elective neck dissection is therefore not recommended.",

keywords = "Adenoid cystic carcinoma, Clinical protocols, Elective neck dissection, Larynx, Lymph node metastasis, Neck, Oncology, Treatment",

author = "Andr{\'e}s Coca-Pelaz and Leon Barnes and Alessandra Rinaldo and Antonio Cardesa and Shah, {Jatin P.} and Rodrigo, {Juan P.} and Carlos Su{\'a}rez and Eloy, {Jean Anderson} and Bishop, {Justin A.} and Devaney, {Kenneth O.} and Thompson, {Lester D.R.} and Wenig, {Bruce M.} and Primo{\v z} Strojan and Marc Hamoir and Bradley, {Patrick J.} and Gnepp, {Douglas R.} and Silver, {Carl E.} and Slootweg, {Pieter J.} and Asterios Triantafyllou and {Vander Poorten}, Vincent and Williams, {Michelle D.} and Alena Sk{\'a}lov{\'a} and Henrik Hellquist and Afshin Teymoortash and Medina, {Jesus E.} and Robbins, {K. Thomas} and Pitman, {Karen T.} and Kowalski, {Luiz P.} and {de Bree}, Remco and Mendenhall, {William M.} and Takes, {Robert P.} and Alfio Ferlito",

note = "Publisher Copyright: {\textcopyright} 2016, The Author(s).",

year = "2016",

month = apr,

day = "1",

doi = "10.1007/s12325-016-0311-z",

language = "English (US)",

volume = "33",

pages = "553--579",

journal = "Advances in Therapy",

issn = "0741-238X",

publisher = "Health Communications Inc.",

number = "4",

}

TY - JOUR

T1 - Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx

T2 - A Collective International Review

AU - Coca-Pelaz, Andrés

AU - Barnes, Leon

AU - Rinaldo, Alessandra

AU - Cardesa, Antonio

AU - Shah, Jatin P.

AU - Rodrigo, Juan P.

AU - Suárez, Carlos

AU - Eloy, Jean Anderson

AU - Bishop, Justin A.

AU - Devaney, Kenneth O.

AU - Thompson, Lester D.R.

AU - Wenig, Bruce M.

AU - Strojan, Primož

AU - Hamoir, Marc

AU - Bradley, Patrick J.

AU - Gnepp, Douglas R.

AU - Silver, Carl E.

AU - Slootweg, Pieter J.

AU - Triantafyllou, Asterios

AU - Vander Poorten, Vincent

AU - Williams, Michelle D.

AU - Skálová, Alena

AU - Hellquist, Henrik

AU - Teymoortash, Afshin

AU - Medina, Jesus E.

AU - Robbins, K. Thomas

AU - Pitman, Karen T.

AU - Kowalski, Luiz P.

AU - de Bree, Remco

AU - Mendenhall, William M.

AU - Takes, Robert P.

AU - Ferlito, Alfio

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to standardize a treatment protocol. One of the controversial points is the decision whether or not to perform an elective neck dissection on these patients. Because there is contradictory information about this issue, we have critically reviewed the literature from 1912 to 2015 on all reported cases of AdCC of the larynx in order to clarify this issue. During the most recent period of our review (1991–2015) with a more exact diagnosis of the tumor histology, 142 cases were observed of AdCC of the larynx, of which 91 patients had data pertaining to lymph node status. Eleven of the 91 patients (12.1%) had nodal metastasis and, based on this low proportion of patients, routine elective neck dissection is therefore not recommended.

AB - Adenoid cystic carcinoma (AdCC) of the head and neck is a well-recognized pathologic entity that rarely occurs in the larynx. Although the 5-year locoregional control rates are high, distant metastasis has a tendency to appear more than 5 years post treatment. Because AdCC of the larynx is uncommon, it is difficult to standardize a treatment protocol. One of the controversial points is the decision whether or not to perform an elective neck dissection on these patients. Because there is contradictory information about this issue, we have critically reviewed the literature from 1912 to 2015 on all reported cases of AdCC of the larynx in order to clarify this issue. During the most recent period of our review (1991–2015) with a more exact diagnosis of the tumor histology, 142 cases were observed of AdCC of the larynx, of which 91 patients had data pertaining to lymph node status. Eleven of the 91 patients (12.1%) had nodal metastasis and, based on this low proportion of patients, routine elective neck dissection is therefore not recommended.

KW - Adenoid cystic carcinoma

KW - Clinical protocols

KW - Elective neck dissection

KW - Larynx

KW - Lymph node metastasis

KW - Neck

KW - Oncology

KW - Treatment

UR - http://www.scopus.com/inward/record.url?scp=84963781849&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84963781849&partnerID=8YFLogxK

U2 - 10.1007/s12325-016-0311-z

DO - 10.1007/s12325-016-0311-z

M3 - Review article

C2 - 27084720

AN - SCOPUS:84963781849

SN - 0741-238X

VL - 33

SP - 553

EP - 579

JO - Advances in Therapy

JF - Advances in Therapy

IS - 4

ER -

Cervical Lymph Node Metastasis in Adenoid Cystic Carcinoma of the Larynx: A Collective International Review

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this