Carpatizine, a novel bridged oxazine derivative generated by non-enzymatic reactions

Peng Fu; John B. MacMillan

doi:10.1039/c7ob01178d

Carpatizine, a novel bridged oxazine derivative generated by non-enzymatic reactions

Peng Fu, John B. MacMillan

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Carpatizine (1), a new bridged oxazine derivative, was isolated from a marine-derived Streptomyces strain SNE-011. The structure was fully determined by spectroscopic analysis, ECD calculations and chemical methods. A plausible non-enzymatic reaction mechanism from daryamide D leading to carpatizine was presented, which was confirmed by chemical transformation.

Original language	English (US)
Pages (from-to)	5275-5278
Number of pages	4
Journal	Organic and Biomolecular Chemistry
Volume	15
Issue number	25
DOIs	https://doi.org/10.1039/c7ob01178d
State	Published - 2017

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c7ob01178d

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title = "Carpatizine, a novel bridged oxazine derivative generated by non-enzymatic reactions",

abstract = "Carpatizine (1), a new bridged oxazine derivative, was isolated from a marine-derived Streptomyces strain SNE-011. The structure was fully determined by spectroscopic analysis, ECD calculations and chemical methods. A plausible non-enzymatic reaction mechanism from daryamide D leading to carpatizine was presented, which was confirmed by chemical transformation.",

author = "Peng Fu and MacMillan, {John B.}",

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PY - 2017

Y1 - 2017

N2 - Carpatizine (1), a new bridged oxazine derivative, was isolated from a marine-derived Streptomyces strain SNE-011. The structure was fully determined by spectroscopic analysis, ECD calculations and chemical methods. A plausible non-enzymatic reaction mechanism from daryamide D leading to carpatizine was presented, which was confirmed by chemical transformation.

AB - Carpatizine (1), a new bridged oxazine derivative, was isolated from a marine-derived Streptomyces strain SNE-011. The structure was fully determined by spectroscopic analysis, ECD calculations and chemical methods. A plausible non-enzymatic reaction mechanism from daryamide D leading to carpatizine was presented, which was confirmed by chemical transformation.

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JO - Organic and Biomolecular Chemistry

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ER -

Carpatizine, a novel bridged oxazine derivative generated by non-enzymatic reactions

Abstract

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