Carotid Arteries: Contrast-enhanced US Angiography-Preliminary Clinical Experience

Yuko Kono; Sean P. Pinnell; Claude B. Sirlin; Steven R. Sparks; Bassem Georgy; Wade Wong; Robert F. Mattrey

doi:10.1148/radiol.2302020318

Carotid Arteries: Contrast-enhanced US Angiography-Preliminary Clinical Experience

Yuko Kono, Sean P. Pinnell, Claude B. Sirlin, Steven R. Sparks, Bassem Georgy, Wade Wong, Robert F. Mattrey

Research output: Contribution to journal › Article › peer-review

88 Scopus citations

Abstract

B-mode ultrasonographic (US) angiography enhanced with a microbubble-based US contrast agent (FS069) was evaluated in human subjects with carotid artery disease. Results at contrast material-enhanced US angiography and duplex US were compared with those at conventional angiography. Both US angiography and duplex US accurately depicted stenoses of 70% or more compared with those depicted at conventional angiography. The percentage diameter stenosis of the internal carotid artery measured at US angiography strongly correlated with that measured at conventional angiography (r = 0.988). The percentage area stenosis measured at US angiography strongly correlated with ex vivo measurements of the resected carotid plaque at magnetic resonance imaging (r = 0.979). US angiography depicted unsuspected wall irregularities, ulceration, and dissection.

Original language	English (US)
Pages (from-to)	561-568
Number of pages	8
Journal	RADIOLOGY
Volume	230
Issue number	2
DOIs	https://doi.org/10.1148/radiol.2302020318
State	Published - Feb 2004

Keywords

Carotid arteries, US
Carotid arteries, stenosis or obstruction
Ultrasound (US), contrast media

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1148/radiol.2302020318

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abstract = "B-mode ultrasonographic (US) angiography enhanced with a microbubble-based US contrast agent (FS069) was evaluated in human subjects with carotid artery disease. Results at contrast material-enhanced US angiography and duplex US were compared with those at conventional angiography. Both US angiography and duplex US accurately depicted stenoses of 70% or more compared with those depicted at conventional angiography. The percentage diameter stenosis of the internal carotid artery measured at US angiography strongly correlated with that measured at conventional angiography (r = 0.988). The percentage area stenosis measured at US angiography strongly correlated with ex vivo measurements of the resected carotid plaque at magnetic resonance imaging (r = 0.979). US angiography depicted unsuspected wall irregularities, ulceration, and dissection.",

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AU - Kono, Yuko

AU - Pinnell, Sean P.

AU - Sirlin, Claude B.

AU - Sparks, Steven R.

AU - Georgy, Bassem

AU - Wong, Wade

AU - Mattrey, Robert F.

PY - 2004/2

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N2 - B-mode ultrasonographic (US) angiography enhanced with a microbubble-based US contrast agent (FS069) was evaluated in human subjects with carotid artery disease. Results at contrast material-enhanced US angiography and duplex US were compared with those at conventional angiography. Both US angiography and duplex US accurately depicted stenoses of 70% or more compared with those depicted at conventional angiography. The percentage diameter stenosis of the internal carotid artery measured at US angiography strongly correlated with that measured at conventional angiography (r = 0.988). The percentage area stenosis measured at US angiography strongly correlated with ex vivo measurements of the resected carotid plaque at magnetic resonance imaging (r = 0.979). US angiography depicted unsuspected wall irregularities, ulceration, and dissection.

AB - B-mode ultrasonographic (US) angiography enhanced with a microbubble-based US contrast agent (FS069) was evaluated in human subjects with carotid artery disease. Results at contrast material-enhanced US angiography and duplex US were compared with those at conventional angiography. Both US angiography and duplex US accurately depicted stenoses of 70% or more compared with those depicted at conventional angiography. The percentage diameter stenosis of the internal carotid artery measured at US angiography strongly correlated with that measured at conventional angiography (r = 0.988). The percentage area stenosis measured at US angiography strongly correlated with ex vivo measurements of the resected carotid plaque at magnetic resonance imaging (r = 0.979). US angiography depicted unsuspected wall irregularities, ulceration, and dissection.

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KW - Carotid arteries, stenosis or obstruction

KW - Ultrasound (US), contrast media

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Carotid Arteries: Contrast-enhanced US Angiography-Preliminary Clinical Experience

Abstract

Keywords

ASJC Scopus subject areas

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