Cardioversion and 'false positive' technetium 99m stannous pyrophosphate myocardial scintigrams

B. R. Pugh, L. M. Buja, R. W. Parkey, L. R. Poliner, E. M. Stokely, F. J. Bonte, J. T. Willerson

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


The present studies performed in experimental animals demonstrate that electrical direct current cardioversion can produce skeletal muscle damage and increased technetium 99m stannous pyrophosphate [99(m)Tc PYP] uptake; in experimental animals the electrically damaged skeletal muscle shows necrosis with extensive calcium deposition. In addition, the frequent administration of high energy cardioversion produces myocardial necrosis with calcium deposition, increased 99(m)Tc PYP myocardial uptake and a positive 99(m)Tc PYP myocardial scintigram. The data indicate that, if diagnostic 99(m)Tc PYP myocardial scintigraphy is contemplated after cardioversion, paddle placement should be slightly removed from the anteroposterior projection of the heart on the external chest wall to avoid possible subsequent confusion between increased myocardial and skeletal muscle uptake of 99(m)Tc PYP. If multiple high energy cardioversion episodes are necessary, myocardial necrosis resulting from electrical injury may occur and be responsible for increased myocardial uptake of 99(m)Tc PYP with a resultant positive 99(m)Tc PYP myocardial scintigram.

Original languageEnglish (US)
Pages (from-to)399-403
Number of pages5
JournalUnknown Journal
Issue number3
StatePublished - 1976

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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