Cardiovascular adaptation to O-G (Experiment 294): Instrumentation for invasive and non-invasive studies

Jay C. Buckey, Lynda D. Lane, Donald E. Watenpaugh, Benjamin D. Levine, Willie E. Moore, F. Andrew Gaffney, C. Gunnar Blomqvist

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Many astronauts returning from space have difficulties regulating blood pressure, some to the point of fainting during quiet standing. Experiment 294 was designed to study this and other cardiovascular effects of adaptation to microgravity and to understand the mechanisms behind it. To accomplish this several cardiovascular variables had to be measured accurately. Heart rate, blood pressure, cardiac output (blood pumped by the heart each minute), stroke volume (blood pumped by the heart with each beat), limb flow, limb compliance, heart size and central venous pressure all had to been recorded during various stresses to understand fully the adaptation to space and the readaptation to earth's gravity. Numerous pieces of equipment were used. Some were purpose-built for the Spacelab mission and others were derived from commercial hardware. Developing spaceflight hardware is challenging and costly, but can lead to significant new information in the unique environment of space.

Original languageEnglish (US)
Title of host publicationSAE Technical Papers
StatePublished - 1991
Event21st International Conference on Environmental Systems - San Francisco, CA, United States
Duration: Jul 15 1991Jul 18 1991


Other21st International Conference on Environmental Systems
Country/TerritoryUnited States
CitySan Francisco, CA

ASJC Scopus subject areas

  • Automotive Engineering
  • Safety, Risk, Reliability and Quality
  • Pollution
  • Industrial and Manufacturing Engineering


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