Cardiac transplantation for pediatric giant cell myocarditis

Bibhuti B. Das; Michael Recto; Christopher Johnsrude; Lisa Klein; Karen Orman; Lawrence Shoemaker; Michael Mitchell; Erle H. Austin

doi:10.1016/j.healun.2005.11.444

Cardiac transplantation for pediatric giant cell myocarditis

Bibhuti B. Das, Michael Recto, Christopher Johnsrude, Lisa Klein, Karen Orman, Lawrence Shoemaker, Michael Mitchell, Erle H. Austin

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.

Original language	English (US)
Pages (from-to)	474-478
Number of pages	5
Journal	Journal of Heart and Lung Transplantation
Volume	25
Issue number	4
DOIs	https://doi.org/10.1016/j.healun.2005.11.444
State	Published - Apr 1 2006

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine
Transplantation

Access to Document

10.1016/j.healun.2005.11.444

Cite this

@article{a2e9e82290a94590ad676ec76f78fe31,

title = "Cardiac transplantation for pediatric giant cell myocarditis",

abstract = "Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.",

author = "Das, {Bibhuti B.} and Michael Recto and Christopher Johnsrude and Lisa Klein and Karen Orman and Lawrence Shoemaker and Michael Mitchell and Austin, {Erle H.}",

year = "2006",

month = apr,

day = "1",

doi = "10.1016/j.healun.2005.11.444",

language = "English (US)",

volume = "25",

pages = "474--478",

journal = "Journal of Heart and Lung Transplantation",

issn = "1053-2498",

publisher = "Elsevier USA",

number = "4",

}

TY - JOUR

T1 - Cardiac transplantation for pediatric giant cell myocarditis

AU - Das, Bibhuti B.

AU - Recto, Michael

AU - Johnsrude, Christopher

AU - Klein, Lisa

AU - Orman, Karen

AU - Shoemaker, Lawrence

AU - Mitchell, Michael

AU - Austin, Erle H.

PY - 2006/4/1

Y1 - 2006/4/1

N2 - Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.

AB - Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.

UR - http://www.scopus.com/inward/record.url?scp=33645049103&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645049103&partnerID=8YFLogxK

U2 - 10.1016/j.healun.2005.11.444

DO - 10.1016/j.healun.2005.11.444

M3 - Article

C2 - 16563980

AN - SCOPUS:33645049103

SN - 1053-2498

VL - 25

SP - 474

EP - 478

JO - Journal of Heart and Lung Transplantation

JF - Journal of Heart and Lung Transplantation

IS - 4

ER -

Cardiac transplantation for pediatric giant cell myocarditis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this