Cardiac transplantation for pediatric giant cell myocarditis

Bibhuti B. Das; Michael Recto; Christopher Johnsrude; Lisa Klein; Karen Orman; Lawrence Shoemaker; Michael Mitchell; Erle H. Austin

doi:10.1016/j.healun.2005.11.444

Cardiac transplantation for pediatric giant cell myocarditis

Bibhuti B. Das, Michael Recto, Christopher Johnsrude, Lisa Klein, Karen Orman, Lawrence Shoemaker, Michael Mitchell, Erle H. Austin

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.

Original language	English (US)
Pages (from-to)	474-478
Number of pages	5
Journal	Journal of Heart and Lung Transplantation
Volume	25
Issue number	4
DOIs	https://doi.org/10.1016/j.healun.2005.11.444
State	Published - Apr 2006

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine
Transplantation

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10.1016/j.healun.2005.11.444

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AU - Das, Bibhuti B.

AU - Recto, Michael

AU - Johnsrude, Christopher

AU - Klein, Lisa

AU - Orman, Karen

AU - Shoemaker, Lawrence

AU - Mitchell, Michael

AU - Austin, Erle H.

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AB - Giant cell myocarditis (GCM) is an organ-specific, autoimmune disease that infrequently affects children and generally has a more aggressive (often fatal) course than other forms of myocarditis. No data are available about the epidemiology of GCM in children. We describe a 13-year-old girl who presented with ventricular tachycardia and rapid hemodynamic deterioration that required extracorporeal membrane oxygenation (ECMO) as a bridge to heart transplantation. Histopathologic examination of the explanted heart revealed GCM. We review the demographic features, clinical course and post-transplant immunosuppressive therapy of all patients aged 19 years and younger reported to have had GCM.

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Cardiac transplantation for pediatric giant cell myocarditis

Abstract

ASJC Scopus subject areas

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