TY - JOUR
T1 - Cardiac resynchronization therapy in patients with chronic atrial fibrillation
AU - Zankar, Ahmad
AU - Joglar, Jose A.
AU - Naseem, R. Haris
PY - 2007/11
Y1 - 2007/11
N2 - Heart failure (HF) and atrial fibrillation (AF), 2 of the most common cardiovascular disorders, often coexist in the same patient, as 1 condition can lead to the other. The best approach to AF management in patients with HF is currently under investigation, but there seems to be an abundance of evidence in support of cardiac resynchronization therapy (CRT) in this group of patients. In addition, CRT is emerging as a superior option to stand-alone right ventricular pacing in patients with structural heart disease. However, in patients with AF, an adequate rate control is critical for this therapy to be highly effective. As control of the ventricular response can be difficult to achieve in many of those patients, often a nonpharmacologic intervention is required, such as ablation of the atrioventricular node to create heart block. The definitive role for CRT with or without atrioventricular nodal ablation in patients with AF and HF is yet to be studied in large, well-designed, randomized, controlled clinical trials.
AB - Heart failure (HF) and atrial fibrillation (AF), 2 of the most common cardiovascular disorders, often coexist in the same patient, as 1 condition can lead to the other. The best approach to AF management in patients with HF is currently under investigation, but there seems to be an abundance of evidence in support of cardiac resynchronization therapy (CRT) in this group of patients. In addition, CRT is emerging as a superior option to stand-alone right ventricular pacing in patients with structural heart disease. However, in patients with AF, an adequate rate control is critical for this therapy to be highly effective. As control of the ventricular response can be difficult to achieve in many of those patients, often a nonpharmacologic intervention is required, such as ablation of the atrioventricular node to create heart block. The definitive role for CRT with or without atrioventricular nodal ablation in patients with AF and HF is yet to be studied in large, well-designed, randomized, controlled clinical trials.
KW - Atrial fibrillation
KW - Cardiac resynchronization
KW - Heart failure
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U2 - 10.1097/CRD.0b013e3181451448
DO - 10.1097/CRD.0b013e3181451448
M3 - Review article
C2 - 18090067
AN - SCOPUS:37349125487
SN - 1061-5377
VL - 15
SP - 310
EP - 315
JO - Cardiology in Review
JF - Cardiology in Review
IS - 6
ER -