Abstract
Calorie restriction, without malnutrition, has been shown to increase longevity and delay the onset of chronic disease in various species. In this chapter, we review the different modalities which scientists and individuals have followed to achieve a sustained caloric deficit. These include traditional dietary restriction regimens of varying degrees, physical activity, alternate day fasting, and alternate day modified fasting. To evaluate the impact of these interventions on chronic disease risk and longevity, we critically evaluate the existing evidence concerning the physiological as well as the behavioral alterations induced by these interventions.
Original language | English (US) |
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Title of host publication | Molecular Basis of Nutrition and Aging |
Subtitle of host publication | A Volume in the Molecular Nutrition Series |
Publisher | Elsevier Inc. |
Pages | 677-692 |
Number of pages | 16 |
ISBN (Electronic) | 9780128018279 |
ISBN (Print) | 9780128018163 |
DOIs | |
State | Published - Apr 28 2016 |
Externally published | Yes |
Keywords
- Aging
- Calorie restriction
- Hormones
- Longevity
- Metabolism
- Physical activity
- Quality of life
- Weight loss
ASJC Scopus subject areas
- Medicine(all)