Brain metastasis from non-seminomatous germ cell tumor of the testis

Jeffrey A. Forquer, Matthew Harkenrider, Achilles J. Fakiris, Robert D. Timmerman, Robert Cavaliere, Mark A. Henderson, Simon S. Lo

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Brain metastasis occurs rarely in patients with testicular cancer in the modern era where cisplatin-based chemotherapy regimens are used. The occurrence of brain metastasis can be synchronous or metachronous (with or without concurrent systemic disease). Long-term survival can be achieved in some patients. The vast majority of testicular cancer cases with brain metastasis reported in the literature involve nonseminomatous germ cell tumor and this subtype will be the focus of this review. This article reviews the literature of the diagnosis and management of brain metastasis from nonseminomatous germ cell tumor of the testis.

Original languageEnglish (US)
Pages (from-to)1567-1580
Number of pages14
JournalExpert Review of Anticancer Therapy
Issue number11
StatePublished - Nov 2007


  • Brain metastasis
  • Germ cell tumor
  • Nonseminomatous
  • Testis

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)


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