Abstract
Purpose: To describe differences in the clinical characteristics of birdshot retinochoroidopathy (BSRC) patients diagnosed early and later in life. Methods: This is a retrospective cohort study. Age was primarily analyzed and 50 years of age at diagnosis was selected as a cut-off point. Results: A total of 144 patients (288 eyes) were included; 68 with early-onset and 76 with late-onset BSRC. The younger group had a statistically significant higher rate of more severe iritis (p = 0.04); an average number of non-steroidal immunosuppressants and biologic agents (NSIB) (p = 0.04); and a prolonged time to initiation of NSIB (p = 0.01). There were only four patients (3%) who had >0.5+ cells in the anterior chamber. Conclusions: Patients with early-onset BSRC carried a higher risk for anterior segment inflammation, had a more prolonged delay to initiation of treatment with NSIB, and required a greater number of NSIBs to achieve remission.
Original language | English (US) |
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Pages (from-to) | 589-595 |
Number of pages | 7 |
Journal | Ocular Immunology and Inflammation |
Volume | 25 |
Issue number | 5 |
DOIs | |
State | Published - Sep 3 2017 |
Keywords
- Birdshot retinochoroidopathy
- early-onset
- inflammation
- late-onset
ASJC Scopus subject areas
- Immunology and Allergy
- Ophthalmology