TY - JOUR
T1 - Bioresorbable polymeric stents
T2 - Current status and future promise
AU - Eberhart, Robert C.
AU - Su, Shih Horng
AU - Nguyen, Kytai Truong
AU - Zilberman, Meital
AU - Tang, Liping
AU - Nelson, Kevin D.
AU - Frenkel, Peter
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2003
Y1 - 2003
N2 - Metal stents and, more recently, polymer-coated metal stents are used to stabilize dissections, eliminate vessel recoil, and guide remodeling after balloon angioplasty and other treatments for arterial disease. Bioresorbable polymeric stents are being developed to improve the biocompatibility and the drug reservoir capacity of metal stents, and to offer a transient alternative to the permanent metallic stent implant. Following a brief review of metal stent technology, the emerging class of expandable, bioresorbable polymeric stents is described, with emphasis on developments in the authors' laboratory.
AB - Metal stents and, more recently, polymer-coated metal stents are used to stabilize dissections, eliminate vessel recoil, and guide remodeling after balloon angioplasty and other treatments for arterial disease. Bioresorbable polymeric stents are being developed to improve the biocompatibility and the drug reservoir capacity of metal stents, and to offer a transient alternative to the permanent metallic stent implant. Following a brief review of metal stent technology, the emerging class of expandable, bioresorbable polymeric stents is described, with emphasis on developments in the authors' laboratory.
KW - Bioresorbable polymeric
KW - Drug delivery
KW - Gene therapy
KW - In-stent restenosis
KW - Stent
UR - http://www.scopus.com/inward/record.url?scp=0038414882&partnerID=8YFLogxK
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U2 - 10.1163/156856203321478838
DO - 10.1163/156856203321478838
M3 - Review article
C2 - 12747671
AN - SCOPUS:0038414882
SN - 0920-5063
VL - 14
SP - 299
EP - 312
JO - Journal of Biomaterials Science, Polymer Edition
JF - Journal of Biomaterials Science, Polymer Edition
IS - 4
ER -