Biomechnical senstivity of the knee joint after ACL-reconstruction surgery

Yasin Y. Dhaher, Shahab Salehghaffari, Malek Adouni

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A computational framework was used to simulate the anterior Cruciate ligament (ACL) reconstructive surgeries, by virtually removing the ACL and then modeling the surgical preparation, tunnel architecture, graft pre-tensioning and fixation angle of a bone-patellar-tendon-bone autograft. To evaluate the relative influence of these surgical factors on the intraoperative joint response a global sensitivity analyses were performed with 48 models. The sensitivity results indicated that the combined variation in tunnel architecture and graft pre-tension at the time of fixation accounts for most of the estimated variance of the two outcomes. Data derived from the 48 ACL reconstructed models indicated that the anatomic surgical design may not be the only design that recovers the healthy joint laxity. In the context of the design of prospective studies, our findings highlight the need to include the graft tension at the time of fixation as a variable in the evaluation of the surgery.

Original languageEnglish (US)
Title of host publication2016 8th Cairo International Biomedical Engineering Conference, CIBEC 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages39-42
Number of pages4
ISBN (Electronic)9781509029877
DOIs
StatePublished - Jan 27 2017
Externally publishedYes
Event8th Cairo International Biomedical Engineering Conference, CIBEC 2016 - Cairo, Egypt
Duration: Dec 15 2016Dec 17 2016

Publication series

Name2016 8th Cairo International Biomedical Engineering Conference, CIBEC 2016

Conference

Conference8th Cairo International Biomedical Engineering Conference, CIBEC 2016
Country/TerritoryEgypt
CityCairo
Period12/15/1612/17/16

Keywords

  • ACL reconstruction
  • Finite Element Model
  • Global Sensitivity Analysis
  • Surgical Variability
  • Surrogate Modeling

ASJC Scopus subject areas

  • Computer Science Applications
  • Biomedical Engineering

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