TY - GEN
T1 - Biomechnical senstivity of the knee joint after ACL-reconstruction surgery
AU - Dhaher, Yasin Y.
AU - Salehghaffari, Shahab
AU - Adouni, Malek
N1 - Publisher Copyright:
© 2016 IEEE.
PY - 2017/1/27
Y1 - 2017/1/27
N2 - A computational framework was used to simulate the anterior Cruciate ligament (ACL) reconstructive surgeries, by virtually removing the ACL and then modeling the surgical preparation, tunnel architecture, graft pre-tensioning and fixation angle of a bone-patellar-tendon-bone autograft. To evaluate the relative influence of these surgical factors on the intraoperative joint response a global sensitivity analyses were performed with 48 models. The sensitivity results indicated that the combined variation in tunnel architecture and graft pre-tension at the time of fixation accounts for most of the estimated variance of the two outcomes. Data derived from the 48 ACL reconstructed models indicated that the anatomic surgical design may not be the only design that recovers the healthy joint laxity. In the context of the design of prospective studies, our findings highlight the need to include the graft tension at the time of fixation as a variable in the evaluation of the surgery.
AB - A computational framework was used to simulate the anterior Cruciate ligament (ACL) reconstructive surgeries, by virtually removing the ACL and then modeling the surgical preparation, tunnel architecture, graft pre-tensioning and fixation angle of a bone-patellar-tendon-bone autograft. To evaluate the relative influence of these surgical factors on the intraoperative joint response a global sensitivity analyses were performed with 48 models. The sensitivity results indicated that the combined variation in tunnel architecture and graft pre-tension at the time of fixation accounts for most of the estimated variance of the two outcomes. Data derived from the 48 ACL reconstructed models indicated that the anatomic surgical design may not be the only design that recovers the healthy joint laxity. In the context of the design of prospective studies, our findings highlight the need to include the graft tension at the time of fixation as a variable in the evaluation of the surgery.
KW - ACL reconstruction
KW - Finite Element Model
KW - Global Sensitivity Analysis
KW - Surgical Variability
KW - Surrogate Modeling
UR - http://www.scopus.com/inward/record.url?scp=85015282778&partnerID=8YFLogxK
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U2 - 10.1109/CIBEC.2016.7836115
DO - 10.1109/CIBEC.2016.7836115
M3 - Conference contribution
AN - SCOPUS:85015282778
T3 - 2016 8th Cairo International Biomedical Engineering Conference, CIBEC 2016
SP - 39
EP - 42
BT - 2016 8th Cairo International Biomedical Engineering Conference, CIBEC 2016
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 8th Cairo International Biomedical Engineering Conference, CIBEC 2016
Y2 - 15 December 2016 through 17 December 2016
ER -