TY - JOUR
T1 - Bath salt intoxication causing acute kidney injury requiring hemodialysis
AU - Regunath, Hariharan
AU - Ariyamuthu, Venkatesh Kumar
AU - Dalal, Pranavkumar
AU - Misra, Madhukar
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/10
Y1 - 2012/10
N2 - Traditional bath salts contain a combination of inorganic salts like Epsom salts, table salt, baking soda, sodium metaphosphate, and borax that have cleansing properties. Since 2010, there have been rising concerns about a new type of substance abuse in the name of "bath salts." They are beta-ketone amphetamine analogs and are derivates of cathinone, a naturally occurring amphetamine analog found in the "khat" plant (Catha edulis). Effects reported with intake included increased energy, empathy, openness, and increased libido. Serious adverse effects reported with intoxication included cardiac, psychiatric, and neurological signs and symptoms. Not much is known about the toxicology and metabolism of these compounds. They inhibit monoamine reuptake (dopamine, nor epinephrine, etc.) and act as central nervous system stimulants with high additive and abuse potential because of their clinical and biochemical similarities to effects from use of cocaine, amphetamine, and 3,4-methylenedioxy-N-methylamphetamine. Deaths associated with use of these compounds have also been reported. We report a case of acute kidney injury associated with the use of "bath salt" pills that improved with hemodialysis.
AB - Traditional bath salts contain a combination of inorganic salts like Epsom salts, table salt, baking soda, sodium metaphosphate, and borax that have cleansing properties. Since 2010, there have been rising concerns about a new type of substance abuse in the name of "bath salts." They are beta-ketone amphetamine analogs and are derivates of cathinone, a naturally occurring amphetamine analog found in the "khat" plant (Catha edulis). Effects reported with intake included increased energy, empathy, openness, and increased libido. Serious adverse effects reported with intoxication included cardiac, psychiatric, and neurological signs and symptoms. Not much is known about the toxicology and metabolism of these compounds. They inhibit monoamine reuptake (dopamine, nor epinephrine, etc.) and act as central nervous system stimulants with high additive and abuse potential because of their clinical and biochemical similarities to effects from use of cocaine, amphetamine, and 3,4-methylenedioxy-N-methylamphetamine. Deaths associated with use of these compounds have also been reported. We report a case of acute kidney injury associated with the use of "bath salt" pills that improved with hemodialysis.
KW - Bath salts
KW - Hemodialysis
KW - Recreational drugs
KW - Renal failure
UR - http://www.scopus.com/inward/record.url?scp=84867177518&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84867177518&partnerID=8YFLogxK
U2 - 10.1111/j.1542-4758.2012.00750.x
DO - 10.1111/j.1542-4758.2012.00750.x
M3 - Article
C2 - 23036036
AN - SCOPUS:84867177518
SN - 1492-7535
VL - 16
SP - S47-S49
JO - Hemodialysis International
JF - Hemodialysis International
IS - SUPPL. 1
ER -