Bacteremia and septic arthritis due to a nontoxigenic strain of Clostridium difficile in a patient with sickle cell disease

Emilie Hill; Adrienne D. Workman; Francesca Lee; Rita Hollaway; Dominick Cavuoti; Bonnie C. Prokesch

doi:10.1093/ofid/ofx278

Bacteremia and septic arthritis due to a nontoxigenic strain of Clostridium difficile in a patient with sickle cell disease

Emilie Hill, Adrienne D. Workman, Francesca Lee, Rita Hollaway, Dominick Cavuoti, Bonnie C. Prokesch

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A 22-year-old female with sickle cell disease presented with fevers, bilateral knee pain, and lethargy. Laboratory data revealed a leukocytosis and lactic acidosis. Blood and synovial fluid cultures grew a non-toxin-producing strain of Clostridium difficile. This case highlights the fact that nontoxigenic Clostridium difficile can cause significant disease.

Original language	English (US)
Article number	ofx278
Journal	Open Forum Infectious Diseases
Volume	5
Issue number	2
DOIs	https://doi.org/10.1093/ofid/ofx278
State	Published - Feb 1 2018

Keywords

Bacteremia
Clostridium difficile
Hemoglobin SS disease
Septic arthritis
Sickle cell disease

ASJC Scopus subject areas

Oncology
Clinical Neurology

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10.1093/ofid/ofx278

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title = "Bacteremia and septic arthritis due to a nontoxigenic strain of Clostridium difficile in a patient with sickle cell disease",

abstract = "A 22-year-old female with sickle cell disease presented with fevers, bilateral knee pain, and lethargy. Laboratory data revealed a leukocytosis and lactic acidosis. Blood and synovial fluid cultures grew a non-toxin-producing strain of Clostridium difficile. This case highlights the fact that nontoxigenic Clostridium difficile can cause significant disease.",

keywords = "Bacteremia, Clostridium difficile, Hemoglobin SS disease, Septic arthritis, Sickle cell disease",

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AU - Workman, Adrienne D.

AU - Lee, Francesca

AU - Hollaway, Rita

AU - Cavuoti, Dominick

AU - Prokesch, Bonnie C.

N1 - Publisher Copyright: © The Author(s) 2018.

PY - 2018/2/1

Y1 - 2018/2/1

N2 - A 22-year-old female with sickle cell disease presented with fevers, bilateral knee pain, and lethargy. Laboratory data revealed a leukocytosis and lactic acidosis. Blood and synovial fluid cultures grew a non-toxin-producing strain of Clostridium difficile. This case highlights the fact that nontoxigenic Clostridium difficile can cause significant disease.

AB - A 22-year-old female with sickle cell disease presented with fevers, bilateral knee pain, and lethargy. Laboratory data revealed a leukocytosis and lactic acidosis. Blood and synovial fluid cultures grew a non-toxin-producing strain of Clostridium difficile. This case highlights the fact that nontoxigenic Clostridium difficile can cause significant disease.

KW - Bacteremia

KW - Clostridium difficile

KW - Hemoglobin SS disease

KW - Septic arthritis

KW - Sickle cell disease

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Bacteremia and septic arthritis due to a nontoxigenic strain of Clostridium difficile in a patient with sickle cell disease

Abstract

Keywords

ASJC Scopus subject areas

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